pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression
about
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1Cell density related gene expression: SV40 large T antigen levels in immortalized astrocyte linesEnumeration of the simian virus 40 early region elements necessary for human cell transformationRegions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.Negative regulation of mitotic promoting factor by the checkpoint kinase chk1 in simian virus 40 lytic infection.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSimian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damageTruncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cellsSomatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.T antigen transformation reveals Tp53/RB-dependent route to PLAC1 transcription activation in primary fibroblasts.J domain independent functions of J proteins.Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.J domain-independent regulation of the Rb family by polyomavirus large T antigenInduction of p53-independent apoptosis by simian virus 40 small t antigen.Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver.A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivoLoss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.
P2860
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P2860
pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
pRB-dependent, J domain-indepe ...... ride of p53 growth suppression
@en
pRB-dependent, J domain-indepe ...... ide of p53 growth suppression.
@nl
type
label
pRB-dependent, J domain-indepe ...... ride of p53 growth suppression
@en
pRB-dependent, J domain-indepe ...... ide of p53 growth suppression.
@nl
prefLabel
pRB-dependent, J domain-indepe ...... ride of p53 growth suppression
@en
pRB-dependent, J domain-indepe ...... ide of p53 growth suppression.
@nl
P2093
P2860
P1433
P1476
pRB-dependent, J domain-indepe ...... ride of p53 growth suppression
@en
P2093
P2860
P304
P356
10.1128/JVI.74.2.864-874.2000
P407
P577
2000-01-01T00:00:00Z