Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways. - sprookjes - yvandenbroek - TriplyDB

Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways.

Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways.

http://www.wikidata.org/entity/Q39646499

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The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone Principles of interleukin (IL)-6-type cytokine signalling and its regulation A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo Interferons and viruses: an evolutionary arms race of molecular interactions Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5 Signal transducer and activator of transcription 5A/B in prostate and breast cancers PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation Real time analysis of STAT3 nucleocytoplasmic shuttling.The human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression.Stat1 nuclear translocation by nucleolin upon monocyte differentiation.Structural and functional studies of STAT1 from Atlantic salmon (Salmo salar).Model-based extension of high-throughput to high-content data.Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3 The cell-specific induction of CXC chemokine ligand 9 mediated by IFN-gamma in microglia of the central nervous system is determined by the myeloid transcription factor PU.1.Rabies virus P protein interacts with STAT1 and inhibits interferon signal transduction pathways.Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.The antihypertension drug doxazosin suppresses JAK/STATs phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis.Clinically relevant dimer interface mutants of STAT1 transcription factor exhibit differential gene expression.STAT1 signaling is not regulated by a phosphorylation-acetylation switch A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites The ins and outs of STAT1 nuclear transport.Diversification of importin-α isoforms in cellular trafficking and disease states DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers.Regulation of Smad activities.Getting the message across, STAT! Design principles of a molecular signaling circuit.DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas.Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads.Nucleocytoplasmic transport blockage by SV40 peptide-modified gold nanoparticles induces cellular autophagy.Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1.Tracking STAT nuclear traffic.Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain

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P2860

Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways.

http://www.wikidata.org/entity/Q39646499

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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2002年论文

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2002年论文

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name

Constitutive and IFN-gamma-ind ...... through independent pathways.

@en

Constitutive and IFN-gamma-ind ...... through independent pathways.

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type

label

Constitutive and IFN-gamma-ind ...... through independent pathways.

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Constitutive and IFN-gamma-ind ...... through independent pathways.

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prefLabel

Constitutive and IFN-gamma-ind ...... through independent pathways.

@en

Constitutive and IFN-gamma-ind ...... through independent pathways.

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P1433

The EMBO Journal

P1476

Constitutive and IFN-gamma-ind ...... through independent pathways.

@en

P2093

Andreas Begitt

http://www.w3.org/2001/XMLSchema#string

Inga Lödige

http://www.w3.org/2001/XMLSchema#string

Marleen van Rossum

http://www.w3.org/2001/XMLSchema#string

Thomas Meyer

http://www.w3.org/2001/XMLSchema#string

Uwe Vinkemeier

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P2860

Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran

The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

How cells respond to interferons

Nucleocytoplasmic transport: the soluble phase

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

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344-354

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10.1093/EMBOJ/21.3.344

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3

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21

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2002-02-01T00:00:00Z

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11537600

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11823427

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125830

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