Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
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Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.The rebel angel: mutant p53 as the driving oncogene in breast cancer.Emerging Non-Canonical Functions and Regulation by p53: p53 and StemnessThe impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasisInactivation and inducible oncogenic mutation of p53 in gene targeted pigsEpithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle?Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cellsAmplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer.RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasisMutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon betaClinical relevance of gain-of-function mutations of p53 in high-grade serous ovarian carcinoma.TP53 mutations detected in circulating tumor cells present in the blood of metastatic triple negative breast cancer patients.Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells.The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation.Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells.Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations.The "Sharp" blade against HIF-mediated metastasis.Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma.Immunoexpression and prognostic role of p53 in different subtypes of epithelial ovarian carcinomaA porcine model of osteosarcoma.Therapeutic targeting of the p53 pathway in cancer stem cells.Caspase-1 is a novel target of p63 in tumor suppression.Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling.Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.p53 and its mutants in tumor cell migration and invasion.Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of TumorigenesisUbiquitination and the Ubiquitin-Proteasome System as regulators of transcription and transcription factors in epithelial mesenchymal transition of cancer.Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis.Epithelial to mesenchymal transition in the pathogenesis of uterine malignant mixed Müllerian tumours: the role of ubiquitin proteasome system and therapeutic opportunities.NRF2 and p53: Januses in cancer?TP53 mutants in the tower of babel of cancer progression.The paradigm of mutant p53-expressing cancer stem cells and drug resistance.Oncogenic roles of EMT-inducing transcription factors.p53 regulates cytoskeleton remodeling to suppress tumor progression.The role of TWIST1 in epithelial-mesenchymal transition and cancers.
P2860
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P2860
Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Mutant p53(R175H) upregulates ...... n immortalized prostate cells.
@en
type
label
Mutant p53(R175H) upregulates ...... n immortalized prostate cells.
@en
prefLabel
Mutant p53(R175H) upregulates ...... n immortalized prostate cells.
@en
P2093
P2860
P356
P1476
Mutant p53(R175H) upregulates ...... in immortalized prostate cells
@en
P2093
A Molchadsky
A Zundelevich
D Sidransky
E N Gal-Yam
I Barshack
P2860
P2888
P304
P356
10.1038/CDD.2010.94
P577
2010-08-06T00:00:00Z