CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).
about
Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus.Characterization of homologous and heterologous rotavirus-specific T-cell responses in infant and adult mice.Identification of Rotavirus VP6-Specific CD4+ T Cell Epitopes in a G1P[8] Human Rotavirus-Infected Rhesus Macaque.Serum IgG mediates mucosal immunity against rotavirus infectionComprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein.The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skinDevelopment of a Bacillus subtilis-based rotavirus vaccineRectal immunization with rotavirus virus-like particles induces systemic and mucosal humoral immune responses and protects mice against rotavirus infection.Heterogeneous memory T cells in antiviral immunity and immunopathologyPrime immunization with rotavirus VLP 2/6 followed by boosting with an adenovirus expressing VP6 induces protective immunization against rotavirus in miceIntrarectal immunization with rotavirus 2/6 virus-like particles induces an antirotavirus immune response localized in the intestinal mucosa and protects against rotavirus infection in mice.Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidatesAlteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice.Autodisplay: development of an efficacious system for surface display of antigenic determinants in Salmonella vaccine strains.Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors.Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in miceInfectious agent and immune response characteristics of chronic enterocolitis in captive rhesus macaquesImmune mediators of rotavirus antigenemia clearance in mice.Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protectionRotavirus infection alters peripheral T-cell homeostasis in children with acute diarrhea.HSV-1 amplicon vectors launch the production of heterologous rotavirus-like particles and induce rotavirus-specific immune responses in miceAn Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8+ T CellsB-Cell-Deficient and CD8 T-Cell-Depleted Gnotobiotic Pigs for the Study of Human Rotavirus Vaccine-Induced Protective Immune ResponsesWhy does the world need another rotavirus vaccine?Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs.Rotavirus vaccines: how they work or don't work.Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblastsDefining T-cell-mediated immune responses in rotavirus-infected juvenile rhesus macaques.Comparative immunogenicity in mice of rotavirus VP6 tubular structures and virus-like particles.Human rotavirus virus-like particle vaccines evaluated in a neonatal gnotobiotic pig model of human rotavirus disease.Understanding internalization of rotavirus VP6 nanotubes by cells: towards a recombinant vaccine.Vaccination with a single CD4 T cell peptide epitope from a Salmonella type III-secreted effector protein provides protection against lethal infection.Rotavirus anti-VP6 secretory immunoglobulin A contributes to protection via intracellular neutralization but not via immune exclusion.Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4(+) T cells following parenteral immunization.Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice.Differential requirements for T cells in viruslike particle- and rotavirus-induced protective immunity.Memory T-cell response to rotavirus detected with a gamma interferon enzyme-linked immunospot assayAssociation of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G).Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM.The Nontoxic Cholera B Subunit Is a Potent Adjuvant for Intradermal DC-Targeted Vaccination
P2860
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P2860
CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
CD4 T cells are the only lymph ...... P6 protein and the adjuvant LT
@nl
CD4 T cells are the only lymph ...... in and the adjuvant LT(R192G).
@en
type
label
CD4 T cells are the only lymph ...... P6 protein and the adjuvant LT
@nl
CD4 T cells are the only lymph ...... in and the adjuvant LT(R192G).
@en
prefLabel
CD4 T cells are the only lymph ...... P6 protein and the adjuvant LT
@nl
CD4 T cells are the only lymph ...... in and the adjuvant LT(R192G).
@en
P2093
P2860
P1433
P1476
CD4 T cells are the only lymph ...... in and the adjuvant LT(R192G).
@en
P2093
Anthony H C Choi
Jason A Flint
John D Clements
John L VanCott
Matili Basu
Monica M McNeal
Richard L Ward
Susan C Stone
P2860
P304
P356
10.1128/JVI.76.2.560-568.2002
P407
P577
2002-01-01T00:00:00Z