Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.
about
Elucidating the immunological function of the Cryptococcus neoformans capsuleChronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatmentReconstructing targetable pathways in lung cancer by integrating diverse omics dataIdentification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell linesTranscriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids.LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients.Dynamic network-based relevance score reveals essential proteins and functional modules in directed differentiation.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesB-Cell Chronic Lymphocytic Leukemia with 11q22.3 Rearrangement in Patient with Chronic Myeloid Leukemia Treated with Imatinib.Antitumor effects of immunotoxins are enhanced by lowering HCK or treatment with SRC kinase inhibitors.Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomasTreatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches.Cryptococcus neoformans galactoxylomannan is a potent negative immunomodulator, inspiring new approaches in anti-inflammatory immunotherapy.Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment.Src family kinases and their role in hematological malignancies.Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types?A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes.Glucocorticoids downregulate Fyn and inhibit IP(3)-mediated calcium signaling to promote autophagy in T lymphocytes.Novel role for p56/Lck in regulation of endothelial cell survival and angiogenesis.Identifying new targets in leukemogenesis using computational approaches.Improvement of dexamethasone sensitivity by chelation of intracellular Ca2+ in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation.Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome.Antitumor activity of antibody against cytotoxic T lymphocyte epitope peptide of lymphocyte-specific protein tyrosine kinase.
P2860
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P2860
Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@en
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@nl
type
label
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@en
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@nl
prefLabel
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@en
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@nl
P2093
P2860
P356
P1476
Inhibition of Lck enhances glu ...... chronic lymphocytic leukemia.
@en
P2093
C W Distelhorst
K S McColl
P2860
P2888
P304
P356
10.1038/CDD.2010.25
P577
2010-03-19T00:00:00Z
P5875
P6179
1026271872