Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction
about
SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptorHepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domainSTAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibitionSimian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5Signaling by STATsViral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-AntagonistsCytopathic and Noncytopathic Interferon Responses in Cells Expressing Hepatitis C Virus Subgenomic RepliconsFunctional annotation of cis-regulatory elements in human cells by dCas9/sgRNASTAT2 deficiency and susceptibility to viral illness in humansHendra and Nipah viruses: different and dangerous.Mumps virus V protein antagonizes interferon without the complete degradation of STAT1.Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys.Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsivenessMapuera virus, a rubulavirus that inhibits interferon signalling in a wide variety of mammalian cells without degrading STATs.Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study.Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference.Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication.Association of mumps virus V protein with RACK1 results in dissociation of STAT-1 from the alpha interferon receptor complex.C-terminal region of STAT-1alpha is not necessary for its ubiquitination and degradation caused by mumps virus V proteinSTAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous systemComposition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain.The amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling.Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signalingSuppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance.Antagonism of innate immunity by paramyxovirus accessory proteins.Trypanosoma cruzi evades the protective role of interferon-gamma-signaling in parasite-infected cells.Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor.HSV-2 inhibits type-I interferon signaling via multiple complementary and compensatory STAT2-associated mechanismsInhibition of interleukin-6 expression by the V protein of parainfluenza virus 5Early induction of interferon-responsive mRNAs in Creutzfeldt-Jakob diseaseProtein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapiesViral modulators of cullin RING ubiquitin ligases: culling the host defense.A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability.
P2860
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P2860
Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
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name
Selective STAT protein degrada ...... interferon signal transduction
@en
Selective STAT protein degrada ...... nterferon signal transduction.
@nl
type
label
Selective STAT protein degrada ...... interferon signal transduction
@en
Selective STAT protein degrada ...... nterferon signal transduction.
@nl
prefLabel
Selective STAT protein degrada ...... interferon signal transduction
@en
Selective STAT protein degrada ...... nterferon signal transduction.
@nl
P2093
P2860
P1433
P1476
Selective STAT protein degrada ...... interferon signal transduction
@en
P2093
Christina M Ulane
Curt M Horvath
Jason J Rodriguez
Jean-Patrick Parisien
P2860
P304
P356
10.1128/JVI.76.9.4190-4198.2002
P407
P577
2002-05-01T00:00:00Z