Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
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Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3Pulmonary metabolism of resveratrol: in vitro and in vivo evidenceStructure and Protein-Protein Interactions of Human UDP-GlucuronosyltransferasesIn vivo and in vitro metabolites from the main diester and monoester diterpenoid alkaloids in a traditional chinese herb, the aconitum speciesResveratrol from transgenic alfalfa for prevention of aberrant crypt foci in miceAnti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cellsPolymorphic expression of UDP-glucuronosyltransferase UGTlA gene in human colorectal cancerUDP-glucuronosyltransferase 1A determinates intracellular accumulation and anti-cancer effect of β-lapachone in human colon cancer cellsDifferential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME.PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2.Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferasesUDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions.A pilot study of leukocyte expression patterns for drug metabolizing enzyme and transporter transcripts in autoimmune glomerulonephritis.Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.UGT2B7 is not expressed in normal breast.Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15Function of UDP-glucuronosyltransferase 2B17 (UGT2B17) is involved in endometrial cancerA genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonatal hyperbilirubinemiaCharacterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification.Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways.Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term.Metabolic pathways of the camptothecin analog AR-67Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United StatesPotential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors.Individual variability in the detoxification of carcinogenic arylhydroxylamines in human breast.Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.The inverse relationship between bladder and liver in 4-aminobiphenyl-induced DNA damage.Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissuesCharacterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases.Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainA signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer.Role of metabolism in the effects of genistein and its phase II conjugates on the growth of human breast cell lines.
P2860
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P2860
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@en
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@nl
type
label
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@en
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@nl
prefLabel
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@en
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.
@nl
P2093
P356
P1476
Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines
@en
P2093
Akiko Nakamura
Hiroyuki Yamanaka
Miki Nakajima
Ryoichi Fujiwara
P304
P356
10.1124/DMD.108.021428
P577
2008-05-14T00:00:00Z