FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.

FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.

Item
http://www.wikidata.org/entity/Q40081796
Wnt/beta-catenin signaling and small molecule inhibitorsVascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon CancerFlt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.Normal bone marrow signal-transduction profiles: a requisite for enhanced detection of signaling dysregulations in AML.Wnt/β-catenin Pathway Modulates the Sensitivity of the Mutant FLT3 Receptor Kinase Inhibitors in a GSK-3β Dependent Manner.Can we safely target the WNT pathway?Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cellsThe GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiationγ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-cateninAll-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.Mechanisms of resistance to FLT3 inhibitors.Adhesive and signaling functions of cadherins and catenins in vertebrate development.Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivityFactors affecting the nuclear localization of β-catenin in normal and malignant tissue.β-catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.Disruption of Wnt/β-catenin exerts anti-leukemia activity and synergizes with FLT3 inhibition in FLT3-mutant acute myeloid leukemia.Y654 of β-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization of β-catenin.
P2860

FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.

Item
http://www.wikidata.org/entity/Q40081796
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
FLT3 regulates beta-catenin ty ...... acute myeloid leukemia cells.
@en
type
label
FLT3 regulates beta-catenin ty ...... acute myeloid leukemia cells.
@en
prefLabel
FLT3 regulates beta-catenin ty ...... acute myeloid leukemia cells.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P6179
P698
P921
P356
P1433
P1476
FLT3 regulates beta-catenin ty ...... acute myeloid leukemia cells.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P6179
P698
P921