The hexameric structure of the human mitochondrial replicative helicase Twinkle. - sprookjes - yvandenbroek - TriplyDB

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

http://www.wikidata.org/entity/Q40176009

about

Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding Novel neuro-audiological findings and further evidence for TWNK involvement in Perrault syndrome.Structure, function and evolution of the animal mitochondrial replicative DNA helicase.Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE.Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.Animal Mitochondrial DNA Replication.Human mitochondrial DNA replication machinery and disease.Inherited mitochondrial genomic instability and chemical exposures.Assessing heterogeneity in oligomeric AAA+ machines.The role of Lon-mediated proteolysis in the dynamics of mitochondrial nucleic acid-protein complexes.Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication

P2860

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P2860

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

http://www.wikidata.org/entity/Q40176009

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

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type

label

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

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prefLabel

The hexameric structure of the human mitochondrial replicative helicase Twinkle.

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Nucleic Acids Research

P1476

The hexameric structure of the human mitochondrial replicative helicase Twinkle

@en

P2093

Claus-A Schmitz

http://www.w3.org/2001/XMLSchema#string

Cristina Silva-Espiña

http://www.w3.org/2001/XMLSchema#string

Nina Rajala

http://www.w3.org/2001/XMLSchema#string

Şirin Cansız-Arda

http://www.w3.org/2001/XMLSchema#string

P2860

TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein

Reconstitution of a minimal mtDNA replisome in vitro

Mechanism and evolution of DNA primases

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis

Modular architecture of the hexameric human mitochondrial DNA helicase

Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7

Structure of the RNA polymerase domain of E. coli primase

Structure of the zinc-binding domain of Bacillus stearothermophilus DNA primase

A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases

Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

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4284-4295

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scholarly article

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10.1093/NAR/GKV189

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8

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43

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Johannes N Spelbrink

Joachim M Gerhold

Pablo Fernández-Millán

Pablo Fernández-Millán

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2015-03-30T00:00:00Z

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274315769

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25824949

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4417153

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