In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2.
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Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathwaysThe complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseActivation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations.LRRK2 Kinase Inhibition as a Therapeutic Strategy for Parkinson's Disease, Where Do We Stand?Pharmacological LRRK2 kinase inhibition induces LRRK2 protein destabilization and proteasomal degradationRegulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease kinases, GTPases, and ATPasesParkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation.Regulation of LRRK2 by Phosphatases.Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design.
P2860
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P2860
In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
In silico, in vitro and cellul ...... o inhibitor activity on LRRK2.
@en
type
label
In silico, in vitro and cellul ...... o inhibitor activity on LRRK2.
@en
prefLabel
In silico, in vitro and cellul ...... o inhibitor activity on LRRK2.
@en
P2093
P2860
P50
P356
P1476
In silico, in vitro and cellul ...... to inhibitor activity on LRRK2
@en
P2093
Fangye Gao
Joren De Raeymaecker
Marc De Maeyer
Renée Vancraenenbroeck
Veerle Baekelandt
P2860
P356
10.3389/FNMOL.2014.00051
P577
2014-06-03T00:00:00Z