Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
about
Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeAPathogenesis of Aspergillus fumigatus in Invasive AspergillosisGliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulenceAspergillus fumigatus: principles of pathogenesis and host defenseAdvances in Aspergillus secondary metabolite research in the post-genomic eraSreA-mediated iron regulation in Aspergillus fumigatusBiosynthesis and function of gliotoxin in Aspergillus fumigatusSCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatusSub-telomere directed gene expression during initiation of invasive aspergillosisOrigin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes.Genomewide screening for genes associated with gliotoxin resistance and sensitivity in Saccharomyces cerevisiae.Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxinRodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization.HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatusA Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence.The cross-pathway control system regulates production of the secondary metabolite toxin, sirodesmin PL, in the ascomycete, Leptosphaeria maculans.Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry.Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulenceCharacterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence.Overview of vertebrate animal models of fungal infection.Antifungal and antihepatotoxic effects of sepia ink extract against oxidative stress as a risk factor of invasive pulmonary aspergillosis in neutropenic miceRNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatusRsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis.Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence.What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?Aspergillus fumigatus and related species.Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesisA novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.Parallels in fungal pathogenesis on plant and animal hosts.Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus.Transcription Factor SomA Is Required for Adhesion, Development and Virulence of the Human Pathogen Aspergillus fumigatus.Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model.The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.A Zn(II)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans.Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis.Aspergillus fumigatus: virulence genes in a street-smart moldHealth effects of Aspergillus in food and air.
P2860
Q21559511-84AF0DBD-44C4-40CD-84A0-DDFA929FA16CQ24650911-6B3BCCB6-BB14-445B-B020-6A318BB40DCBQ24673051-38940DD7-B01E-4B8C-96B0-F34D7F6620BDQ24681995-84971D07-C68C-4170-A567-D091A37A3F17Q26823169-D5ED9C06-4462-42FD-8EEF-13FFA3AF44F9Q27976506-D04C4CCC-76C9-4AE9-A7D9-24E49142F8FDQ28253295-5600D57A-E0ED-450E-A8F5-FDD55009AF22Q28554262-381D4612-5492-4E41-906D-30F9FB6E4B9CQ30847680-ECCEEB07-6B3C-4BE3-B040-B95ED23F3976Q33300473-8239818D-2084-4111-AA5D-1D131060C5DDQ33315756-70BB6F37-CF41-4F45-9843-E87F916AF817Q33604870-3D22E487-0E82-414D-81D7-0BCF3FC8E2EEQ33689767-2DC3FA79-D421-40BE-9206-A41E8280FC5DQ33716978-108A09D5-EDE7-4C5D-8156-0CC234F00BF3Q33916498-75187B7B-BFAC-4388-880C-E75837055484Q33963128-4CEFF63C-6897-4E61-85F8-1E520F4DF8D8Q33972033-EF772929-BB79-4549-9842-5F3404C6F522Q34006202-1B5F9EEB-1E0A-4061-84AD-BA4A1AF2D69CQ34064545-67CB6F44-8BD2-483A-B354-1C6956D125F3Q34163742-B08B1B02-7827-42F6-91C8-A35D5E535F14Q34175500-F5E55A28-6481-4985-AD27-9A9E2D5CAC24Q34367333-4F88B602-3206-4DCA-9E59-F6DFBF59110FQ34402038-6125BBC0-47BC-4919-ADB1-58FAADE91FA2Q34720671-A34B25AC-70F0-4F29-BC3C-CED47F342533Q34736784-1DD2C8CE-DDCF-4872-B697-255F9DE270E2Q34793495-55E3C934-4B48-467D-9ECA-3DFEB5621847Q35045054-CF84D008-22F5-45E1-AEBE-F3E3233DF346Q35150476-79F00A96-4803-4AA4-9B1B-A2A430A0A08EQ35160549-77B09119-2200-43FD-A9A6-567ECE13B0C0Q35216760-1C5BED09-162F-437E-984C-353196678459Q35587757-F5516717-7113-4182-9EB6-88E45BA49061Q35830582-465967A7-F4F1-4AA2-906C-AD1309FB284EQ36095263-36A3F555-60C7-4B66-93DA-53E593D93F03Q36095285-B8AF33CE-2A5C-436B-9013-868567CF8CE1Q36313729-13ABE2C4-B3F1-429E-8A8A-2BF4CD33247AQ36362395-9B774E8E-E6AC-466A-90C5-8859E598513AQ36683779-2CAA8755-8401-4030-BDA1-F7E6921D0AC3Q36755328-5B7EAA44-B74D-4646-AC28-534784D1C24CQ37200064-72ACCA26-0D43-4F6D-A093-49C8D4886213Q37606121-336EA93A-50CA-4AE9-911E-75A6B9CAD988
P2860
Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Deletion of the gliP gene of A ...... ow-dose mouse infection model.
@en
type
label
Deletion of the gliP gene of A ...... ow-dose mouse infection model.
@en
prefLabel
Deletion of the gliP gene of A ...... ow-dose mouse infection model.
@en
P2093
P2860
P1476
Deletion of the gliP gene of A ...... ow-dose mouse infection model.
@en
P2093
Albert Härtl
Axel A Brakhage
Claudio Kupfahl
Gernot Geginat
Herbert Hof
Thomas Ruppert
P2860
P304
P356
10.1111/J.1365-2958.2006.05373.X
P407
P577
2006-08-31T00:00:00Z