The transcriptional repressor hDaxx potentiates p53-dependent apoptosis. - sprookjes - yvandenbroek - TriplyDB

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

http://www.wikidata.org/entity/Q40520539

about

Critical role for Daxx in regulating Mdm2 MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis FTH1 binds to Daxx and inhibits Daxx-mediated cell apoptosis p53 mediates the negative regulation of MDM2 by orphan receptor TR3 Transcriptional activation of the adenoviral genome is mediated by capsid protein VI Adenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells Phylogeny and function of the invertebrate p53 superfamily Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.Oncolytic vesicular stomatitis virus induces apoptosis via signaling through PKR, Fas, and Daxx.Methylation of RASSF1A gene promoter is regulated by p53 and DAXX.Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection.Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.p53-family proteins and their regulators: hubs and spokes in tumor suppression.Virion factors that target Daxx to overcome intrinsic immunity.EBNA3C regulates p53 through induction of Aurora kinase B.Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.Daxx is a transcriptional repressor of CCAAT/enhancer-binding protein beta A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells.Acidic domains: "converse readers" for acetylation code.Structural basis for DAXX interaction with ATRX.Daxx-beta and Daxx-gamma, two novel splice variants of the transcriptional co-repressor Daxx.Daxx-like protein of Drosophila interacts with Dmp53 and affects longevity and Ark mRNA level.Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.Requirement for Daxx in mature T-cell proliferation and activation.E1B-55K mediated regulation of RNF4 STUbL promotes HAdV gene expression.Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.

P2860

Q24297332-21AC0E7C-2A3F-4B9F-9104-06FB84812BAF Q24297439-A5B9F0F5-FF52-44B7-8740-F9CF3F2C2DF7 Q24300728-051F1DA2-0013-463D-8186-48D0CF2389A0 Q24302497-F2A6701B-E883-4775-93C6-D4135830CF05 Q24321873-16F5CC9B-A6EE-4356-A16D-CDE19939358D Q27347199-E6C6D260-1988-463D-8DD3-0A08299BE998 Q28574947-78C3C29F-20F3-458B-910D-3BBA3AD0D974 Q28751278-2EBA12A6-DAD5-4ACE-923F-A0854C0D6CEE Q30833310-5F794F5F-07DB-41F2-9734-0A9AA94D3EBA Q34393712-3E970EAD-45A3-4F4B-AEE6-4A8C35A7D153 Q35158045-FDEB51EF-8E08-400F-8F45-D681B4E093B7 Q35784861-B4F1F1BC-9B83-4C59-9B62-2F9767BFDBD5 Q36482906-5E802A93-1ACB-4952-A25A-8D27C21EE6AE Q36607020-F26A8B9A-CDCA-4162-82E2-41261412CA6A Q36667990-6DBCE37E-F2D0-40DE-B2BB-529C6950A2A5 Q37727778-043B3988-A96F-4C6D-99CC-9F012DF024F6 Q38122355-827FDA96-62C7-4869-A18F-7589A8DD74D3 Q38908573-772F8F78-29B0-4E84-9BFA-A121FB00519F Q39196984-EE00AF4F-8ACF-404C-88F2-3ADBC5EBFB52 Q39299722-DD47D6B2-8936-4347-95C9-C48ADEEA8625 Q39428299-5A20A0D7-85F4-4DF6-B236-6F8A4CE27AC9 Q39677755-B0DD1809-0CBD-46DF-ACF1-3202AF4D07C7 Q39702317-DA94634E-55F9-45E7-B4D8-39673738F2C1 Q42316737-1CA56EFD-66E7-4405-A5FC-98AE9B29157B Q42704636-0EB2E99F-0D60-495D-927C-26294F60DEDA Q42740314-01A5AC9D-0C1D-4321-B81E-ECEA7D58EC5A Q47071260-EA027F15-020A-46B9-A145-07C86E1A70F5 Q51679220-EC24C6A4-311A-4745-AC3F-D06B63706472 Q52002852-E8067AAD-0184-4548-A6B7-9C1986EAEF83 Q52309606-6685CAB9-04DA-46DE-AD22-F98CB339E1ED Q55026448-99A70427-88F3-40F5-80F5-DD9E2259E3B7

P2860

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

http://www.wikidata.org/entity/Q40520539

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

2004年论文

@zh

2004年论文

@zh-cn

name

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

@en

type

label

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

@en

prefLabel

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

@en

P1433

Q40520539-9C378218-1679-4385-85D2-0BC6DC50C3C3

P1476

Q40520539-B0D3FC9C-7D8C-457A-B7E0-DCAA8DDE582D

P2093

Q40520539-0756E528-0198-4F85-8060-8FD036DB09EE

Q40520539-2AECB16C-9F47-4CFE-B90C-8253CC550496

Q40520539-501B73A5-459F-49E4-8293-FB99BE86F127

Q40520539-509E9B4A-4781-4055-8161-98AA3367085B

Q40520539-76B282E4-CEF7-497F-B46A-58B28512C8FC

Q40520539-93613C44-0821-424C-BE90-F67DDF7A230E

Q40520539-A3E73206-62F7-4A79-95DA-9E8FBD5E0CA2

Q40520539-C1D4B6DF-49C0-4A41-85FD-2FCEA7821667

Q40520539-E912DDC7-741B-471B-AF33-58FF096E33B0

P2860

Q40520539-0418EEF4-0B4F-4A7E-85C7-5825A646536A

Q40520539-09079653-132D-4CD3-9491-5FC062C6FF73

Q40520539-0F682231-BA6E-4E8C-91CE-C4BD3FBAEED7

Q40520539-13B05E11-53C3-4EA9-9B90-F6D69790A3F3

Q40520539-159F3BFB-4A24-40BC-B6CC-DB7A34BEA49C

Q40520539-1A4BDCC8-C20A-4A46-8200-6A83AA178E2D

Q40520539-1E2933B1-563D-4818-ACB7-2B5756AAFA60

Q40520539-2414341A-B4F4-4002-B53B-30C7E4F5D042

Q40520539-26992889-525E-4D71-A53D-83994AF9125E

Q40520539-3269CC72-B5B5-4D8F-B791-D78188809F94

P304

Q40520539-11338726-3B58-4CD2-80D8-6ECA688BE748

P31

Q40520539-C387D138-BC87-4AC8-B4C1-B305197346EF

P356

Q40520539-562B885E-BD99-4E6F-A9A1-4D8F9402319D

P407

Q40520539-B80CCE9E-48AD-4E64-89C7-6C9F17222D21

P433

Q40520539-E34D77A0-4567-45E7-81D5-4B14D8EED219

P478

Q40520539-8DFC2697-2700-4551-85B2-FFC0B289517B

P577

Q40520539-4C9573C3-AEE1-472F-BC4C-30CB97418D26

P698

Q40520539-6AC037A8-D8B9-471D-9DE5-85A89F29B8B1

P356

P1433

Journal of Biological Chemistry

P1476

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

@en

P2093

Claudio Brancolini

http://www.w3.org/2001/XMLSchema#string

Claudio Schneider

http://www.w3.org/2001/XMLSchema#string

Elisa Guida

http://www.w3.org/2001/XMLSchema#string

Fiamma Mantovani

http://www.w3.org/2001/XMLSchema#string

Giannino Del Sal

http://www.w3.org/2001/XMLSchema#string

Licio Collavin

http://www.w3.org/2001/XMLSchema#string

Manuela Morelli

http://www.w3.org/2001/XMLSchema#string

Monica Gostissa

http://www.w3.org/2001/XMLSchema#string

Silvano Piazza

http://www.w3.org/2001/XMLSchema#string

P2860

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation

Regulation of p53 activity in nuclear bodies by a specific PML isoform

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm

ASPP proteins specifically stimulate the apoptotic function of p53

The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells

P304

48013-48023

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M310801200

http://www.w3.org/2001/XMLSchema#string

P407

P433

46

http://www.w3.org/2001/XMLSchema#string

P478

279

http://www.w3.org/2001/XMLSchema#string

P577

2004-08-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15339933

http://www.w3.org/2001/XMLSchema#string