P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.
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Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2Clinical Implications of P-Glycoprotein Modulation in Drug-Drug Interactions.Challenges of using in vitro data for modeling P-glycoprotein efflux in the blood-brain barrier.Methods to assess drug permeability across the blood-brain barrier.Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies.Quantitative structure activity relationship for inhibition of human organic cation/carnitine transporter.Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.The Effects of Cetirizine on P-glycoprotein Expression and Function In vitro and In situPredictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children.Drug metabolism and pharmacokinetics.Why clinical modulation of efflux transport at the human blood-brain barrier is unlikely: the ITC evidence-based position.New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors.Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier.P-gp inhibition potential in cell-based models: which "calculation" method is the most accurate?Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig.Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.The role of P-glycoprotein in CNS antihistamine effects.Determination of the unbound fraction of R- and S-methadone in human brain.Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment.
P2860
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P2860
P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
P-glycoprotein influences the ...... on non-sedating antihistamine.
@en
type
label
P-glycoprotein influences the ...... on non-sedating antihistamine.
@en
prefLabel
P-glycoprotein influences the ...... on non-sedating antihistamine.
@en
P2093
P356
P1476
P-glycoprotein influences the ...... ion non-sedating antihistamine
@en
P2093
Angela L Mote
Cosette J Serabjit-Singh
Jo A Salisbury
Joan E Humphreys
Kelly H Jordan
Timothy K Tippin
Todd M Baughman
P304
P356
10.1002/JPS.10453
P407
P577
2003-10-01T00:00:00Z