Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives.
about
The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.Prioritizing Hits with Appropriate Trade-Offs Between HIV-1 Reverse Transcriptase Inhibitory Efficacy and MT4 Blood Cells Toxicity Through Desirability-Based Multiobjective Optimization and Ranking.Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase.Current state-of-the-art in preclinical and clinical development of novel non-nucleoside HIV-1 reverse transcriptase inhibitors
P2860
Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Design, synthesis, SAR, and mo ...... thiazolylthiourea derivatives.
@en
type
label
Design, synthesis, SAR, and mo ...... thiazolylthiourea derivatives.
@en
prefLabel
Design, synthesis, SAR, and mo ...... thiazolylthiourea derivatives.
@en
P2093
P356
P1476
Design, synthesis, SAR, and mo ...... thiazolylthiourea derivatives.
@en
P2093
Andrea Spallarossa
Angelo Ranise
Francesco Bondavalli
Laura Vargiu
Massimo Mura
Olga Bruno
Paolo La Colla
Silvia Schenone
Tiziana Marceddu
P304
P356
10.1021/JM0209984
P407
P577
2003-02-01T00:00:00Z