Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
about
The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical OverviewExpansion of CD4+ T cells with a cytotoxic phenotype in patients with B-chronic lymphocytic leukaemia (B-CLL)Roles of Host Nonhematopoietic Cells in Autoimmunity and Donor Cell Engraftment in Graft-versus-host Disease.Advances in lupus stemming from the parent-into-F1 modelDonor CD8 T cell activation is critical for greater renal disease severity in female chronic graft-vs.-host mice and is associated with increased splenic ICOS(hi) host CD4 T cells and IL-21 expressionPerforin-mediated target-cell death and immune homeostasis.Cytolytic pathways in haematopoietic stem-cell transplantation.Implications of the parent-into-F1 model for human lupus pathogenesis: roles for cytotoxic T lymphocytes and viral pathogens.Therapeutic potential of CD8+ cytotoxic T lymphocytes in SLEDonor CD8 T cells and IFN-gamma are critical for sex-based differences in donor CD4 T cell engraftment and lupus-like phenotype in short-term chronic graft-versus-host disease mice.Enhancement of suboptimal CD8 cytotoxic T cell effector function in vivo using antigen-specific CD80 defective T cells.Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host diseaseSuppression of lymphoma and epithelial malignancies effected by interferon gammaProteasome inhibition and allogeneic hematopoietic stem cell transplantation: a reviewPresentation of hemophagocytic lymphohistiocytosis due to a novel MUNC 13-4 mutation masked by partial therapeutic immunosuppression.Regulatory T cells in lupus.T cells, murine chronic graft-versus-host disease and autoimmunity.Murine models of chronic graft-versus-host disease: insights and unresolved issues.In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-versus-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor.CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus.Mouse models of bone marrow transplantationRevisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes.Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses.Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease.The Parent-into-F1 Model of Graft-vs-Host Disease as a Model of In Vivo T Cell Function and Immunomodulation.Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupusPleiotropic targets: the problem of shared signaling circuitry in rheumatoid arthritis disease progression and protection.Modulation of the spleen transcriptome in domestic turkey (Meleagris gallopavo) in response to aflatoxin B1 and probiotics.Association of mixed hematopoietic chimerism with elevated circulating autoantibodies and chronic graft-versus-host disease occurrence.Vincristine-cyclophosphamide combination therapy positively affects T-cell subset distribution in systemic lupus erythematosus patients.The strength of B cell immunity in female rhesus macaques is controlled by CD8+ T cells under the influence of ovarian steroid hormones.Peripheral blood cytotoxic lymphocyte gene transcript levels differ in patients with long-term type 1 diabetes compared to normal controls.CD8+ immunoregulatory cells in the graft-versus-host reaction: CD8 T cells activate dendritic cells to secrete interleukin-12/interleukin-18 and induce T helper 1 autoantibody.CTL-Promoting Effects of IL-21 Counteract Murine Lupus in the Parent→F1 Graft-versus-Host Disease Model.
P2860
Q28066083-6CB16A26-59A3-495F-B70E-BE3D5C7C3CC4Q28362584-F6C147B5-5865-4F2E-AA8C-BF5535517D71Q33896432-A5C025FB-2243-4692-8FE1-FB57D5828DC4Q33903169-F2518F23-2FFE-4806-BA66-7AA58DCDA372Q33967652-80B9BF3F-D8D7-4529-9C1F-C621519ABBC1Q34584322-7222AFFA-75D1-4E40-BC94-83166ACA25B4Q34632083-84FA6C15-6142-461B-979E-2C78F15F2D1CQ35479272-E6856E45-B2FE-46E7-B3D8-53F7C48B05BAQ35547592-E8392E53-1C90-47F9-B441-9730684870D3Q35547605-F3FFD888-C2DD-427B-ABA1-214560EAA08DQ35580588-F0BC9E1B-CA09-4F96-A8C9-EEC9DD2B0548Q35605610-15E3222F-4BE0-4397-9F8B-D739CBB83956Q36371115-F793D195-F563-41B0-9453-69FF34FEA977Q36408216-7DDF023F-D286-4F21-8B8E-FBF0763AEF83Q36416172-2C221B64-13E4-449C-920F-FE8D6B5AB7F7Q36419022-7C19DFB7-2415-4176-B651-753D2C4C7CD0Q36626989-BCD5E9A6-FAD0-425B-BE6C-24775F619D13Q36645730-1339053C-0D82-46D6-B2F6-8E59BA7BD0B8Q36788495-EC07F789-707D-4E3F-81E4-5264D9DB4C8FQ37034711-7F88C63E-9EEA-4BF1-AF54-2507D8A0B5D3Q37045969-7374D38A-93C5-4E73-A6AF-47BFE59CE228Q37270151-06ECCF05-2D21-4561-A10E-1A67CF29BEACQ37305254-D9263D67-89B1-40FC-96D7-2C627392E41CQ37398338-46F893CA-FDFF-487A-8913-524B2B05C710Q37401090-D1494561-CF32-4FB1-8B99-E5D1110CE8D8Q37444305-1EC7CDE6-3876-4454-B48D-95A92C2EB040Q38005191-9E0CE459-F485-4CF1-96CC-620B8ABCDAC3Q41536641-8812B9AE-7F10-44B1-841C-DD8AD4444240Q42152223-9B9B94DF-AB4C-4D4D-9D97-5B251CBB4156Q43156580-20CFD368-0C52-4F29-859F-0AE9DE77CB04Q43975326-150FEBF1-A19A-40DD-A2EC-FF1AF27A0E46Q46717647-83A1BEC5-95D1-4B7F-BA6B-90370F4FB98BQ47749765-49D60855-C3BA-43BE-8DF0-B444E25266CCQ48065880-8F4021AF-55DE-48FB-BB7F-C685BAC3721A
P2860
Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
@en
type
label
Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
@en
prefLabel
Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
@en
P2093
P2860
P356
P1476
Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.
@en
P2093
B Handwerger
J C Papadimitriou
P2860
P304
P356
10.1172/JCI8876
P407
P577
2000-09-01T00:00:00Z