p53 and recombination intermediates: role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation.
about
Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.DNA end joining becomes less efficient and more error-prone during cellular senescence.Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targetsDNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.Probing potential binding modes of the p53 tetramer to DNA based on the symmetries encoded in p53 response elements.Chromosome instability and deregulated proliferation: an unavoidable duo.A truncated p53 in human lung cancer cells as a critical determinant of proliferation and invasiveness.DNA substrate dependence of p53-mediated regulation of double-strand break repair.Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells.Association of p53 and MSH2 with recombinative repair complexes during S phase.Wild-type p53 inhibits replication-associated homologous recombination.p53 protects from replication-associated DNA double-strand breaks in mammalian cells.
P2860
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P2860
p53 and recombination intermediates: role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
p53 and recombination intermed ...... nd exonucleolytic degradation.
@en
type
label
p53 and recombination intermed ...... nd exonucleolytic degradation.
@en
prefLabel
p53 and recombination intermed ...... nd exonucleolytic degradation.
@en
P2093
P2860
P356
P1433
P1476
p53 and recombination intermed ...... nd exonucleolytic degradation.
@en
P2093
Christine Janz
Lisa Wiesmüller
Silke Süsse
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205292
P407
P577
2002-03-01T00:00:00Z
P5875
P6179
1035014210