Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung.
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Proteoglycan form and function: A comprehensive nomenclature of proteoglycansInhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARARoles of Proteoglycans and Glycosaminoglycans in Wound Healing and FibrosisAlways cleave up your mess: targeting collagen degradation to treat tissue fibrosisBiological interplay between proteoglycans and their innate immune receptors in inflammationThe wound healing, chronic fibrosis, and cancer progression triadT Cell Interstitial Migration: Motility Cues from the Inflamed Tissue for Micro- and Macro-PositioningOxidative stress and glutathione in TGF-beta-mediated fibrogenesisAsporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast CancerTargeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung FibroblastsRegional heterogeneity in murine lung fibroblasts from normal mice or mice exposed once to cigarette smokeTumour necrosis factor-alpha interacts with biglycan and decorin.Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiologyControlled and uncontrolled asthma display distinct alveolar tissue matrix compositions.Transforming growth factor-β (TGF-β) expression is increased in the subsynovial connective tissues of patients with idiopathic carpal tunnel syndrome.Extracellular matrix regulation of inflammation in the healthy and injured spinal cordSoluble biglycan as a biomarker of inflammatory renal diseases.Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity.Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts.Transforming growth factor-β2 is sequestered in preterm human milk by chondroitin sulfate proteoglycansDecorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissueFibromodulin-deficiency alters temporospatial expression patterns of transforming growth factor-β ligands and receptors during adult mouse skin wound healing.Renal accumulation of biglycan and lipid retention accelerates diabetic nephropathy.The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3Novel insights into the function and dynamics of extracellular matrix in liver fibrosis.Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction.Idiopathic pulmonary fibrosis: current understanding of the pathogenesis and the status of treatmentDecreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.The small leucine-rich repeat proteoglycans in tissue repair and atherosclerosisLactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-βProteoglycan and collagen expression during human air conducting system development.Extracellular matrix remodeling: the common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure.Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases.Upregulation of decorin by FXR in vascular smooth muscle cells.Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate.Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis.Matrix Remodeling in Pulmonary Fibrosis and Emphysema.Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract
P2860
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P2860
Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Proteoglycans decorin and bigl ...... ibrotic responses in the lung.
@en
type
label
Proteoglycans decorin and bigl ...... ibrotic responses in the lung.
@en
prefLabel
Proteoglycans decorin and bigl ...... ibrotic responses in the lung.
@en
P2093
P2860
P1476
Proteoglycans decorin and bigl ...... ibrotic responses in the lung.
@en
P2093
P2860
P304
P356
10.1152/AJPLUNG.2001.280.6.L1327
P577
2001-06-01T00:00:00Z