Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs. - sprookjes - yvandenbroek - TriplyDB

Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs.

Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs.

http://www.wikidata.org/entity/Q40945559

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In vitro and in vivo effects of doxycycline on Toxoplasma gondii Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.Survival of treponemes after treatment: comments, clinical conclusions, and recommendations.Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia Pharmacokinetics of sparfloxacin in the serum and vitreous humor of rabbits: physicochemical properties that regulate penetration of quinolone antimicrobials.Pharmacokinetics of doxycycline in dogs.Anatomical barriers for antimicrobial agents.Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine.Penetration of doxycycline into cerebrospinal fluid in patients treated for suspected Lyme neuroborreliosis.Penetration of oral doxycycline into the cerebrospinal fluid of patients with latent or neurosyphilis.Role of oxygen radicals in the phototoxicity of tetracyclines toward Escherichia coli B Side effects of minocycline: a double-blind study.Synergistic activity of clarithromycin and minocycline in an animal model of acute experimental toxoplasmosis Minocycline: far beyond an antibiotic.Chronic oral administration of minocycline to sheep with ovine CLN6 neuronal ceroid lipofuscinosis maintains pharmacological concentrations in the brain but does not suppress neuroinflammation or disease progression CNS inflammation and bone marrow neuropathy in type 1 diabetes.Agents for the decolonization of methicillin-resistant Staphylococcus aureus.Minocycline attenuates iron neurotoxicity in cortical cell cultures.Mechanisms of action of systemic antibiotics used in periodontal treatment and mechanisms of bacterial resistance to these drugs.Managing Rocky Mountain spotted fever.Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature.Tetracycline compounds with non-antimicrobial organ protective properties: possible mechanisms of action.The significance of matrix metalloproteinase (MMP)-2 and MMP-9 in the ischemic stroke.Update in feline therapeutics: clinical use of 10 emerging therapies.Combination of minocycline and rifampicin against methicillin- and gentamicin-resistant Staphylococcus aureus.Modern neurosyphilis: a partially treated chronic meningitis.Effect of tetracyclines and UV light on oxygen consumption by human leukocytes Rationale for optimal dosing of beta-lactam antibiotics in therapy for bacterial meningitis.Bacterial resistance to the tetracyclines.Cetocycline, tetracycline analog: in vitro studies of antimicrobial activity, serum binding, lipid solubility, and uptake by bacteria.Pharmacokinetics of minocycline in domestic cats.Susceptibility to antimicrobials of mastitis-causing Staphylococcus aureus, Streptococcus uberis and Str. dysgalactiae from New Zealand and the USA as assessed by the disk diffusion test.Pharmacodynamics of doxycycline and tetracycline against Staphylococcus pseudintermedius: proposal of canine-specific breakpoints for doxycycline.The effect of doxycycline hyclate, chlorhexidine gluconate, and minocycline hydrochloride on osteoblastic proliferation and differentiation in vitro.Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes.Pain in amyotrophic lateral sclerosis: a neglected aspect of disease Influence of tetracyclines on human polymorphonuclear leukocyte function.Antipsychotic-like effect of minocycline in a rat model.Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation.

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Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs.

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1975 nî lūn-bûn

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Barza M

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Brown RB

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Distribution and excretion of four tetracycline analogues in normal young men.

Lipophilic character and biological activity of drugs. II. The parabolic case.

Pharmacokinetics and molecular modification: implications in drug design and evaluation.

Some pharmacokinetic aspects of doxycycline metabolism in man.

Pharmacokinetic studies on minocycline in man.

[Kinetics of tetracyclines in human. II. Excretion, penetration into normal and inflammed tissues, behavior in a case of renal insufficiency and in hemodialysis]

Metabolism and tissue distribution of radioisotopically labelled minocycline.

Extraction of antibiotics from the circulation by liver and kidney: effect of probenecid.

The distribution of tetracyclines in tissues of dogs after repeated oral administration.

Intestinal juice level of various antibiotics administered parenterally.

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