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Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapyOpen Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondProfound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodesIn Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria Box Reveals Novel Compounds with Profound Activities against Theileria annulata SchizontsExpression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family.Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggsNew approaches for the identification of drug targets in protozoan parasites.A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizontsBuparvaquone is active against Neospora caninum in vitro and in experimentally infected mice.In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninumRepurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse modelDi-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice.In vitro culture systems for the study of apicomplexan parasites in farm animals.Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole.In vitro screening of the open source Pathogen Box identifies novel compounds with profound activities against Neospora caninum.Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models.Drug target identification in protozoan parasites.Thioureides of 2-(phenoxymethyl)benzoic acid 4-R substituted: a novel class of anti-parasitic compounds.Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells.Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis.Two Novel Calcium-Dependent Protein Kinase 1 Inhibitors Interfere with Vertical Transmission in Mice Infected with Neospora caninum Tachyzoites.Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin.Dose-dependent effects of experimental infection with the virulent Neospora caninum Nc-Spain7 isolate in a pregnant mouse model.The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX.In vitro effects of new artemisinin derivatives in Neospora caninum-infected human fibroblasts.PrP-C1 fragment in cattle brains reveals features of the transmissible spongiform encephalopathy associated PrPsc.Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes.Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin.Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites.Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs.Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii.Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole.Identification of a host cell target for the thiazolide class of broad-spectrum anti-parasitic drugsIn Vitro Activities of MMV Malaria Box Compounds against the Apicomplexan Parasite Neospora caninum, the Causative Agent of Neosporosis in AnimalsComparative proteomics of three Giardia lamblia strains: Investigation of antigenic variation in the post-genomic eraNeospora caninum: Structure and Fate of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294Neospora caninum: Differential Proteome of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294
P50
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P50
description
hulumtues
@sq
onderzoeker
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researcher
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հետազոտող
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name
Joachim Müller
@ast
Joachim Müller
@en
Joachim Müller
@es
Joachim Müller
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type
label
Joachim Müller
@ast
Joachim Müller
@en
Joachim Müller
@es
Joachim Müller
@sl
prefLabel
Joachim Müller
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Joachim Müller
@en
Joachim Müller
@es
Joachim Müller
@sl
P106
P21
P31
P496
0000-0001-8189-9270