Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle.

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Vitamin D3 intake modulates diaphragm but not peripheral muscle force in young mice.

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Q36902236-4CE221FF-65A7-4048-AFED-6CB6F1EB11A9

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Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle.

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Hyperactive mTORC1 signaling i ...... tment in aged skeletal muscle.

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Hyperactive mTORC1 signaling i ...... tment in aged skeletal muscle.

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Hyperactive mTORC1 signaling i ...... tment in aged skeletal muscle.

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Hyperactive mTORC1 signaling i ...... tment in aged skeletal muscle.

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Cory M Dungan

http://www.w3.org/2001/XMLSchema#string

David C Wright

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David L Williamson

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Zhuyun Li

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Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

Metformin activates AMP kinase through inhibition of AMP deaminase

Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

TSC2 mediates cellular energy response to control cell growth and survival

Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

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107-117

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scholarly article

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10.1002/MUS.24698

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2015-04-29T00:00:00Z

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25926238

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metformin

Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle.

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P2860

P2860

Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle.

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P1476

P2093

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P921

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