Glycogenolysis in astrocytes supports blood-borne glucose channeling not glycogen-derived lactate shuttling to neurons: evidence from mathematical modeling.
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Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular levelRole of Glycogenolysis in Memory and Learning: Regulation by Noradrenaline, Serotonin and ATPLactate transport and signaling in the brain: potential therapeutic targets and roles in body-brain interactionUnraveling the complex metabolic nature of astrocytesIs L-lactate a novel signaling molecule in the brain?Contributions of glycogen to astrocytic energetics during brain activation.Brain lactate metabolism: the discoveries and the controversies.Fueling and imaging brain activation.Monoaminergic Control of Cellular Glucose Utilization by Glycogenolysis in Neocortex and Hippocampus.Molecular basis of impaired glycogen metabolism during ischemic stroke and hypoxiaThe role of astrocytic glycogen in supporting the energetics of neuronal activityAstrocyte-neuron lactate transport is required for long-term memory formation.Does abnormal glycogen structure contribute to increased susceptibility to seizures in epilepsy?Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective.Insulin and Insulin-like Growth Factor 1 (IGF-1) Modulate Cytoplasmic Glucose and Glycogen Levels but Not Glucose Transport across the Membrane in Astrocytes.Brain glycogen content and metabolism in subjects with type 1 diabetes and hypoglycemia unawareness.Regulation of cerebral metabolism during cortical spreading depression.Sweet sixteen for ANLS.Schwann cell glycogen selectively supports myelinated axon function.Glucose metabolism down-regulates the uptake of 6-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (6-NBDG) mediated by glucose transporter 1 isoform (GLUT1): theory and simulations using the symmetric four-state carrier model.Kinetic analysis of glycogen turnover: relevance to human brain 13C-NMR spectroscopy.Lactate Shuttles in Neuroenergetics-Homeostasis, Allostasis and Beyond.Why does the brain (not) have glycogen?Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source.Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation.Glycogen function in adult central and peripheral nerves.Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA.Pluralistic roles for glycogen in the central and peripheral nervous systems.Astrocyte glycogen as an emergency fuel under conditions of glucose deprivation or intense neural activity.Functional impact of glycogen degradation on astrocytic signalling.Role of the Astrocytic Na(+), K(+)-ATPase in K(+) Homeostasis in Brain: K(+) Uptake, Signaling Pathways and Substrate Utilization.Computational Flux Balance Analysis Predicts that Stimulation of Energy Metabolism in Astrocytes and their Metabolic Interactions with Neurons Depend on Uptake of K+ Rather than Glutamate.Glycogen: Multiple Roles in the CNS.Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte-neuron lactate shuttle in brain.Emerging Roles for Glycogen in the CNS.Imaging of a glucose analog, calcium and NADH in neurons and astrocytes: dynamic responses to depolarization and sensitivity to pioglitazone.Modelling of pH dynamics in brain cells after stroke.Determination of Glucose Utilization Rates in Cultured Astrocytes and Neurons with [14C]deoxyglucose: Progress, Pitfalls, and Discovery of Intracellular Glucose Compartmentation.Astrocytes are 'good scouts': being prepared also helps neighboring neuronsIs lactate a volume transmitter of metabolic states of the brain?
P2860
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P2860
Glycogenolysis in astrocytes supports blood-borne glucose channeling not glycogen-derived lactate shuttling to neurons: evidence from mathematical modeling.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Glycogenolysis in astrocytes s ...... ce from mathematical modeling.
@en
type
label
Glycogenolysis in astrocytes s ...... ce from mathematical modeling.
@en
prefLabel
Glycogenolysis in astrocytes s ...... ce from mathematical modeling.
@en
P2093
P2860
P50
P356
P1476
Glycogenolysis in astrocytes s ...... nce from mathematical modeling
@en
P2093
Bruno Maraviglia
Federico Giove
Mauro DiNuzzo
Silvia Mangia
P2860
P304
P356
10.1038/JCBFM.2010.151
P577
2010-09-08T00:00:00Z