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Stronger is not always better: could a bodybuilding dietary supplement lead to ALS?Mechanisms of glutamate transportReview of pharmacological treatment in mood disorders and future directions for drug development.Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to dateDeveloping Medications Targeting Glutamatergic Dysfunction in Autism: Progress to DateDrug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs.Checkpoints to the Brain: Directing Myeloid Cell Migration to the Central Nervous SystemProgressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment OptionsThe complex molecular biology of amyotrophic lateral sclerosis (ALS)Advances in the treatment of anxiety: targeting glutamate.Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.Optimizing care of patients with ALS. Steps to early detection and improved quality of life.Lack of riluzole efficacy in the progression of the neurodegenerative phenotype in a new conditional mouse model of striatal degeneration.Redox modifier genes and pathways in amyotrophic lateral sclerosis.Modelling amyotrophic lateral sclerosis: progress and possibilitiesPreclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptomsMetal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS.Updated report on tools to measure outcomes of clinical trials in fragile X syndrome.Intramolecular Rearrangement of α-Amino Acid Amide Derivatives of 2-AminobenzothiazolesPathological correlations between traumatic brain injury and chronic neurodegenerative diseases.A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?Riluzole protects against cardiac ischaemia and reperfusion damage via block of the persistent sodium current.Mechanisms, models and biomarkers in amyotrophic lateral sclerosisp38 MAP kinase-mediated NMDA receptor-dependent suppression of hippocampal hypersynchronicity in a mouse model of Alzheimer's diseaseFamilial amyotrophic lateral sclerosis.Riluzole But Not Melatonin Ameliorates Acute Motor Neuron Degeneration and Moderately Inhibits SOD1-Mediated Excitotoxicity Induced Disrupted Mitochondrial Ca2+ Signaling in Amyotrophic Lateral SclerosisChemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanomaRiluzole pharmacokinetics in young patients with spinal muscular atrophy.Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzoleEffect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvantEffects of depolarizing stimuli on calcium homeostasis in cultured rat motoneuronesEfficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.Increased survival and reinnervation of cervical motoneurons by riluzole after avulsion of the C7 ventral rootRegulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system.Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology.Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model.Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial.Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis painThe preclinical discovery of amyotrophic lateral sclerosis drugs.The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats.
P2860
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P2860
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The pharmacology and mechanism of action of riluzole.
@en
type
label
The pharmacology and mechanism of action of riluzole.
@en
prefLabel
The pharmacology and mechanism of action of riluzole.
@en
P1433
P1476
The pharmacology and mechanism of action of riluzole.
@en
P2093
P304
P356
10.1212/WNL.47.6_SUPPL_4.233S
P407
P433
P577
1996-12-01T00:00:00Z