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Structural basis of substrate discrimination and integrin binding by autotaxinInhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphateAnticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling.Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progressionThe ins and outs of lysophosphatidic acid signaling.Regulation and biological activities of the autotaxin-LPA axis.Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organizationAutotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosisTGF-β receptor signaling pathways in angiogenesis; emerging targets for anti-angiogenesis therapy.Vascular endothelial growth factor B controls endothelial fatty acid uptake.Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during developmentENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis.Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine.Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma.NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation.Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.Upregulation of cytokine expression in fibroblasts exposed to loxosceles sphingomyelinase D: what is the trigger?
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Laurens A van Meeteren
@ast
Laurens A van Meeteren
@en
Laurens A van Meeteren
@es
Laurens A van Meeteren
@nl
Laurens A van Meeteren
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type
label
Laurens A van Meeteren
@ast
Laurens A van Meeteren
@en
Laurens A van Meeteren
@es
Laurens A van Meeteren
@nl
Laurens A van Meeteren
@sl
prefLabel
Laurens A van Meeteren
@ast
Laurens A van Meeteren
@en
Laurens A van Meeteren
@es
Laurens A van Meeteren
@nl
Laurens A van Meeteren
@sl
P1053
A-9890-2008
P106
P21
P31
P3829
P496
0000-0001-9885-0668