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Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detectionPredicting response to epigenetic therapyQuality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRMLimitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies.Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancerHypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma.Genotyping common FSHR polymorphisms based on competitive amplification of differentially melting amplicons (CADMA)Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes.Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome PatientsWhole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome.Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in GlioblastomaTumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations.Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing.Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphomaDNA methylation, epimutations and cancer predisposition.PCR-based methods for detecting single-locus DNA methylation biomarkers in cancer diagnostics, prognostics, and response to treatment.Epigenetics and cancer treatment.Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases.Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma.Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes.Competitive amplification of differentially melting amplicons (CADMA) enables sensitive and direct detection of all mutation types by high-resolution melting analysis.Increased sensitivity of KRAS mutation detection by high-resolution melting analysis of COLD-PCR products.Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma.Hypomethylation and increased expression of the putative oncogene ELMO3 are associated with lung cancer development and metastases formation.Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutationsELMO3: a direct driver of cancer metastasis?The challenges of comparing a clinically validated test to other methods.Direct genotyping of single nucleotide polymorphisms in methyl metabolism genes using probe-free high-resolution melting analysis.Circular RNAs in cancer: opportunities and challenges in the field.Circular RNAs are abundantly expressed and upregulated during human epidermal stem cell differentiation.DNA Methylation Levels of the ELMO Gene Promoter CpG Islands in Human Glioblastomas.Allele-Specific DNA Methylation Detection by Pyrosequencing®.Analysis of epigenetic modifications of DNA in human cells.A role for immunohistochemical detection of BRAF V600E prior to BRAF-inhibitor treatment of malignant melanoma?Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and MalignancyPublisher Correction: Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutationsMethylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNPA comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinomaEnzyme-free digital counting of endogenous circular RNA molecules in B-cell malignanciesHigh-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Lasse Sommer Kristensen
@ast
Lasse Sommer Kristensen
@en
Lasse Sommer Kristensen
@es
Lasse Sommer Kristensen
@sl
type
label
Lasse Sommer Kristensen
@ast
Lasse Sommer Kristensen
@en
Lasse Sommer Kristensen
@es
Lasse Sommer Kristensen
@sl
prefLabel
Lasse Sommer Kristensen
@ast
Lasse Sommer Kristensen
@en
Lasse Sommer Kristensen
@es
Lasse Sommer Kristensen
@sl
P106
P1153
24278618100
P21
P31
P496
0000-0002-5980-7939