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The agr Inhibitors Solonamide B and Analogues Alter Immune Responses to Staphylococccus aureus but Do Not Exhibit Adverse Effects on Immune Cell FunctionsSelectively N-protected enantiopure 2,5-disubstituted piperazines: avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations.Chemotaxonomy of Plantago. Iridoid glucosides and caffeoyl phenylethanoid glycosides.Bacterial membrane activity of α-peptide/β-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains.High in vitro antimicrobial activity of β-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis.Chemotaxonomy of the Oleaceae: iridoids as taxonomic markers.Adaptive evolution of Escherichia coli to an α-peptide/β-peptoid peptidomimetic induces stable resistance.Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii.Iminolactones as tools for inversion of the absolute configuration of α-amino acids and as inhibitors of cancer cell proliferation.Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation.A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coliGlycopeptide mimics of mammalian Man9GlcNAc2. Ligand binding to mannan-binding proteins (MBPs).Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivoBlock of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition.Nano-Self-Assemblies Based on Synthetic Analogues of Mycobacterial Monomycoloyl Glycerol and DDA: Supramolecular Structure and Adjuvant Efficacy.Engineering of small interfering RNA-loaded lipidoid-poly(DL-Lactic-Co-Glycolic Acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach.Conserved Molecular Superlattices in a Series of Homologous Synthetic Mycobacterial Cell-Wall Lipids Forming Interdigitated Bilayers.Adjuvants Based on Synthetic Mycobacterial Cord Factor Analogues: Biophysical Properties of Neat Glycolipids and Nanoself-Assemblies with DDA.Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: enhanced gene silencing and reduced adverse effects in vitro.The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase.Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells.Soft hydrogels interpenetrating silicone--A polymer network for drug-releasing medical devices.Anti-inflammatory Properties of Antimicrobial Peptides and Peptidomimetics: LPS and LTA Neutralization.An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action.Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs and antibiotics against human pathogenic bacteria.Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices.Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.End group modification: Efficient tool for improving activity of antimicrobial peptide analogues towards Gram-positive bacteria.Conjugation of cell-penetrating peptides to parathyroid hormone affects its structure, potency, and transepithelial permeation.Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo.Influence of trehalose 6,6'-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes.Lipidated α-peptide/β-peptoid hybrids with potent anti-inflammatory activity.Lysine-Based α-Peptide/β-Peptoid Peptidomimetics: Influence of Hydrophobicity, Fluorination, and Distribution of Cationic Charge on Antimicrobial Activity and Cytotoxicity.Cellular uptake and membrane-destabilising properties of alpha-peptide/beta-peptoid chimeras: lessons for the design of new cell-penetrating peptides.Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin.Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists.Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A.A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues.Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.
P50
Q28552024-1EB61CA8-F749-4A1C-9202-B9803C0570C6Q33405302-680D6004-A074-45CF-8DEE-736F6753B695Q33928211-E30E0208-F730-4804-90D7-7EEDA4DBEA72Q33938698-4AB42F75-6847-488D-896C-905E783AA051Q34478691-37C22CCB-5045-403A-A305-0499DD89249CQ34657762-858F2278-2F9F-4B0B-A07F-6F6E2D4A077FQ34989010-12E6B7C3-7AEF-4D05-9141-29C141705916Q35575367-E37FB041-D42B-4ACD-99BD-41C28B03FB24Q35956035-04F5F614-3FCB-4968-955E-A1299E52C884Q35967870-8522E8F7-489B-41D5-8579-8F027999B72CQ36085645-D34EA575-AA52-4087-9D48-2F2F9C2D768DQ36843663-0238078C-6630-4012-98BC-4C38E57F8EB9Q37398283-E84CC4EA-BB8E-47B9-8DCF-227C78B2F80FQ37454237-C2A5D47E-E473-4A01-8208-67C95BEF42CCQ37836037-D19BA2BF-1BAB-4FBE-9EC1-314F2E026746Q38653466-084BE6A6-F582-4436-BBF7-E7C9851946BDQ38785230-8A552418-6482-4007-9AEF-5D90D08F825CQ38789792-21DFEA7D-5DB2-4662-9723-0520D734FED5Q38820640-42F85411-CBDC-4A2A-B44E-1DB866FB2AF0Q38841316-88803F5E-8572-4FE9-AA4D-BC3D26D295AAQ38907461-D1FCA614-03FF-4687-A7FA-3A2F94661AD4Q39016279-405687A6-4648-4701-818C-8B020D47304EQ39066110-410713BF-1E45-4C90-B125-931CDFADA9FFQ40315976-1867B793-C82E-472B-85D2-BD79FFF30509Q40395301-0B311067-376D-4F44-9796-599C4C0F4268Q41193812-C7522701-BCBA-4E57-8057-C9443206A939Q41208099-EB0804E3-C724-49E6-B942-D128E4234A5AQ41521459-63711E13-7C59-4D0A-B965-75C8666339FDQ41528430-082B7E32-01D0-484B-B3CF-198847C55FA9Q41603361-BD9E47FB-AF23-459D-85F9-DEDDD7DD8513Q41617405-CA31ED42-7236-4ABD-80CB-1638F961E058Q41637254-CC4E7476-6F4B-42E1-8E2C-37390F201BBDQ41712108-B0699B20-736C-4AB9-9EB1-8829248C57DAQ42804043-774DAC01-3ABB-4E55-817B-DF138E01D873Q42809968-D80098F9-67D6-4DE9-AE99-FB477CB6BCCEQ42829020-189899E8-6CB3-4236-96C9-37FD478DA5C1Q42875596-A4EB55E8-5A69-44A3-A236-1B9CCD6C9F4BQ43980381-25993A2E-42FA-4D25-BC39-840B800CCC3EQ44320491-5BF33B9C-D45D-4748-ABD5-99A1EF5D1BF5Q44707685-DB463B19-78F5-42BF-8E3D-D874CDD8C949
P50
description
Deens onderzoeker
@nl
hulumtues
@sq
researcher
@en
հետազոտող
@hy
name
Henrik Franzyk
@ast
Henrik Franzyk
@en
Henrik Franzyk
@es
Henrik Franzyk
@nl
Henrik Franzyk
@sl
type
label
Henrik Franzyk
@ast
Henrik Franzyk
@en
Henrik Franzyk
@es
Henrik Franzyk
@nl
Henrik Franzyk
@sl
prefLabel
Henrik Franzyk
@ast
Henrik Franzyk
@en
Henrik Franzyk
@es
Henrik Franzyk
@nl
Henrik Franzyk
@sl
P106
P1153
7003941562
P21
P27
P31
P3835
henrik-franzyk
P496
0000-0002-2822-1927