Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
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Impaired mitochondrial dynamics and bioenergetics in diabetic skeletal muscleThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsMG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signallingInsulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory phenomenon.Reciprocal regulation of endocytosis and metabolismEffects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer.Hydrogen peroxide primes heart regeneration with a derepression mechanism.Muscle wasting: an overview of recent developments in basic research.TRIM72 is required for effective repair of alveolar epithelial cell wounding.Myeloperoxidase deletion prevents high-fat diet-induced obesity and insulin resistance.Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function.Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase.Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity.Effect of metabolic syndrome on mitsugumin 53 expression and function.Zinc Binding to MG53 Protein Facilitates Repair of Injury to Cell MembranesUric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic DisordersNox2 mediates skeletal muscle insulin resistance induced by a high fat dietCardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury.MG53-mediated cell membrane repair protects against acute kidney injuryMitoflash altered by metabolic stress in insulin-resistant skeletal muscle.Membrane Repair: Mechanisms and Pathophysiology.MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle.Cardiovascular research is thriving in China.The neuropilin-like protein ESDN regulates insulin signaling and sensitivity.Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy.MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels.Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat DietMitsugumin 53 (MG53) ligase ubiquitinates focal adhesion kinase during skeletal myogenesis.Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization.Signaling pathways controlling skeletal muscle massUbiquitination in disease pathogenesis and treatment.Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation.MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress.Diabetic cardiomyopathy: role of the E3 ubiquitin ligase.Role of E3 ubiquitin ligases in insulin resistance.Dual function of MG53 in membrane repair and insulin signaling.Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation.Ubiquitination and the Regulation of Membrane Proteins.
P2860
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P2860
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
@en
type
label
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
@en
prefLabel
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
@en
P2093
P2860
P921
P356
P1433
P1476
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
@en
P2093
Chun-Mei Cao
Fenghua Liu
Fengxiang Lv
Hong-Kun Wu
Jiaojiao Guo
Peng Jiang
Ping Jiang
Rui-Ping Xiao
P2860
P2888
P304
P356
10.1038/NATURE11834
P407
P577
2013-01-27T00:00:00Z
P5875
P6179
1032061039