Triggering co-stimulation directly in melanoma tumor fragments drives CD8(+) tumor-infiltrating lymphocyte expansion with improved effector-memory properties.

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Detection of Productively Rearranged TcR-α V-J Sequences in TCGA Exome Files: Implications for Tumor Immunoscoring and Recovery of Antitumor T-cells.S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity.

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Triggering co-stimulation directly in melanoma tumor fragments drives CD8(+) tumor-infiltrating lymphocyte expansion with improved effector-memory properties.

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2015 nî lūn-bûn

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Triggering co-stimulation dire ...... ed effector-memory properties.

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Triggering co-stimulation dire ...... ed effector-memory properties.

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Amod A Sarnaik

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Jessica Ann Chacon

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Laszlo Radvanyi

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Shari Pilon-Thomas

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Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production

CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor.

Interferon gamma is required for activation-induced death of T lymphocytes.

Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

Immune regulation by 4-1BB and 4-1BBL: complexities and challenges.

Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy.

Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves.

Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy.

IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.

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10.1080/2162402X.2015.1040219

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Triggering co-stimulation directly in melanoma tumor fragments drives CD8(+) tumor-infiltrating lymphocyte expansion with improved effector-memory properties.

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P2860

P2860

Triggering co-stimulation directly in melanoma tumor fragments drives CD8(+) tumor-infiltrating lymphocyte expansion with improved effector-memory properties.

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