Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum
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Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malariaEvidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial AgentsInhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusionOn the mechanism of chloroquine resistance in Plasmodium falciparumChloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.Predictive computational models of substrate binding by a nucleoside transporter.An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparumEvolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South AmericaInhibition of intramacrophage growth of Penicillium marneffei by 4-aminoquinolines.PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.Membrane transport in the malaria-infected erythrocyte.Emerging targets for antimalarial drugs.Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.Therapy of falciparum malaria in sub-saharan Africa: from molecule to policy.The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice.Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum.Molecular and physiologic basis of quinoline drug resistance in Plasmodium falciparum malariaInhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamersChloroquine transport in Plasmodium falciparum. 2. Analysis of PfCRT-mediated drug transport using proteoliposomes and a fluorescent chloroquine probe.Quantification of labile heme in live malaria parasites using a genetically encoded biosensorTarget identification and validation of novel antimalarials.Role of Different Pfcrt and Pfmdr-1 Mutations in Conferring Resistance to Antimalaria Drugs in Plasmodium falciparum.Heme binding contributes to antimalarial activity of bis-quaternary ammoniums.Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.Potent enhancement of the sensitivity of Plasmodium falciparum to chloroquine by the bisbenzylisoquinoline alkaloid cepharanthin.Role of the neurotransmitter reuptake-blocking activity of antidepressants in reversing chloroquine resistance in vitro in Plasmodium falciparum.In vitro increase in chloroquine accumulation induced by dihydroethano- and ethenoanthracene derivatives in Plasmodium falciparum-parasitized erythrocytesChemosensitization of Plasmodium falciparum by probenecid in vitro.Role of Plasmodium falciparum digestive vacuole plasmepsins in the specificity and antimalarial mode of action of cysteine and aspartic protease inhibitors.Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparumAn attenuated total reflection (ATR) and Raman spectroscopic investigation into the effects of chloroquine on Plasmodium falciparum-infected red blood cells.Chloroquine transport in Plasmodium falciparum. 1. Influx and efflux kinetics for live trophozoite parasites using a novel fluorescent chloroquine probe.Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum.Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter.Analysis of the antimalarial drug resistance protein Pfcrt expressed in yeast.Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes.Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin.Plasmodium falciparum Na+/H+ exchanger activity and quinine resistance.The role of Plasmodium falciparum food vacuole plasmepsins.X-ray structure of plasmepsin II complexed with a potent achiral inhibitor.
P2860
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P2860
Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Cellular uptake of chloroquine ...... ivity in Plasmodium falciparum
@en
type
label
Cellular uptake of chloroquine ...... ivity in Plasmodium falciparum
@en
prefLabel
Cellular uptake of chloroquine ...... ivity in Plasmodium falciparum
@en
P2093
P2860
P356
P1476
Cellular uptake of chloroquine ...... ivity in Plasmodium falciparum
@en
P2093
P2860
P304
P356
10.1083/JCB.145.2.363
P407
P577
1999-04-01T00:00:00Z