Different distribution of morphine and morphine-6 beta-glucuronide after intracerebroventricular injection in rats.

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Role of morphine's metabolites in analgesia: concepts and controversies.Mapping of endogenous morphine-like compounds in the adult mouse brain: Evidence of their localization in astrocytes and GABAergic cells.

P2860

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P2860

Different distribution of morphine and morphine-6 beta-glucuronide after intracerebroventricular injection in rats.

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http://www.wikidata.org/entity/Q42113228

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2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Different distribution of morp ...... ventricular injection in rats.

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Different distribution of morp ...... ventricular injection in rats.

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type

Item

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Different distribution of morp ...... ventricular injection in rats.

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Different distribution of morp ...... ventricular injection in rats.

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Different distribution of morp ...... ventricular injection in rats.

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Different distribution of morp ...... ventricular injection in rats.

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P1476

Different distribution of morp ...... ventricular injection in rats.

@en

P2093

Aki Fujii

http://www.w3.org/2001/XMLSchema#string

Masanori Saito

http://www.w3.org/2001/XMLSchema#string

Misato Nakanishi

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Noriyuki Komiyama

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Ryohei Kimura

http://www.w3.org/2001/XMLSchema#string

Shizuo Yamada

http://www.w3.org/2001/XMLSchema#string

Takashi Okura

http://www.w3.org/2001/XMLSchema#string

P2860

Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling

Prediction of in vivo tissue distribution from in vitro data 1. Experiments with markers of aqueous spaces.

Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs.

Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium.

Morphine-6 beta-glucuronide has a higher efficacy than morphine as a mu-opioid receptor agonist in the rat locus coeruleus

Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology.

Pharmacokinetic modelling of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid of neurosurgical patients after short-term infusion of morphine.

Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test.

Elevated concentrations of morphine 6-beta-D-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability.

Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine.

P304

211-217

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scholarly article

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10.1038/SJ.BJP.0705418

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English

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140

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2003-08-04T00:00:00Z

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10572946

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12967951

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1574014

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Different distribution of morphine and morphine-6 beta-glucuronide after intracerebroventricular injection in rats.

about

P2860

P2860

Different distribution of morphine and morphine-6 beta-glucuronide after intracerebroventricular injection in rats.

description

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P1433

P1476

P2093

P2860

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P5875

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P2093

P2860

P304

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P478

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P932