Cyclin dependent kinase inhibitor 1A

Cyclin dependent kinase inhibitor 1A

Item
http://www.wikidata.org/entity/Q423686
CDKN1A
P688
Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicityInvolvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell linesTelomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)Feedback between p21 and reactive oxygen production is necessary for cell senescenceE3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradationCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsSelective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.The cyclin-dependent kinase inhibitors p15INK4B and p21CIP1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrestPCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.New functional activities for the p21 family of CDK inhibitorsCleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascadeThe p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesHDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanismOncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4aDNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblastsTranslational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient StressCyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase deltaStructural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversityTRIM39 regulates cell cycle progression and DNA damage responses via stabilizing p21.The hypoxia-induced microRNA-130a controls pulmonary smooth muscle cell proliferation by directly targeting CDKN1A.CDK inhibitors, p21(Cip1) and p27(Kip1), participate in cell cycle exit of mammalian cardiomyocytes
P921
Q36804509-A36BDF93-C501-4B45-9737-F494295E2369Q50250530-07440787-010C-4DF5-B512-D2096FE41550Q50250782-A3693EC8-B332-46E5-84FE-4F2222DEA0B3Q50250786-82B6B271-44F7-4F0E-B289-069CE99B8945Q50250799-54FF4CF6-E947-47CC-9076-44749B90D1C5Q50250842-1A1706A2-A872-4F15-99ED-4AF4A961C2D4Q50250843-2378930D-60AB-44E5-8C25-F493146A9936Q50250851-7F20BC47-1536-46EC-B8BB-C2DA60D9E298Q50251181-4808BEE4-4090-480C-BB63-E7B5ED676D76Q50263046-66AFFB7D-A368-4EBE-850B-8CA30D7A6C8DQ50285982-D42B4DB6-8726-4F68-AB99-9D4FA973EADCQ50285982-DA8C20AB-6808-42A4-93E6-7AA3CCA88CCDQ50286170-67DFE5C5-818E-4018-9F1F-869E435976F1Q50286947-0A92ED5D-BBCD-4F13-9AFB-D6915383BE0FQ50290448-664431C5-1B13-442E-9069-61F290ADC89DQ50290674-6A07CA17-7B17-46AD-9531-101B6CAFF663Q50290738-74C73E2E-02C9-4019-AB2C-4A299E96BF2FQ50290740-80158C77-8491-4D69-A6A3-9ACAFECB01D6
P527

Cyclin dependent kinase inhibitor 1A

Item
http://www.wikidata.org/entity/Q423686
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in P21
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
CDK-Inhibitor 1
@de
CDKN1A
@cy
CDKN1A
@uk
Cyclin dependent kinase inhibitor 1A
@en
P21
@cs
P21
@es
P21
@fi
P21
@fr
P21
@id
P21
@it
type
label
CDK-Inhibitor 1
@de
CDKN1A
@cy
CDKN1A
@uk
Cyclin dependent kinase inhibitor 1A
@en
P21
@cs
P21
@es
P21
@fi
P21
@fr
P21
@id
P21
@it
altLabel
Białko p21
@pl
CDK-interacting protein 1
@en
CDK-interaction protein 1
@en
CDKN1A
@en
CDKN1A
@es
CDKN1A
@it
CDKN1A
@pl
DNA synthesis inhibitor
@en
MDA-6
@en
Melanoma differentiation-associated protein 6
@en
prefLabel
CDK-Inhibitor 1
@de
CDKN1A
@cy
CDKN1A
@uk
Cyclin dependent kinase inhibitor 1A
@en
P21
@cs
P21
@es
P21
@fi
P21
@fr
P21
@id
P21
@it
P2888
P31
P352
P361
P486
P637
P638
P646
P680
P681
P682
P702
P703
P705
P352
P486
P637
P638
P646
P2888
P31
P352
P361
P486
P637
P638
P646
P680
P681
P682
P702
P703
P705