Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.
about
Directed evolution of P-glycoprotein cysteines reveals site-specific, non-conservative substitutions that preserve multidrug resistance.Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis.Reaction dynamics of ATP hydrolysis catalyzed by P-glycoprotein.Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.Functional analysis of ABCB4 mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity.
P2860
Q33802134-BF6E6095-F722-47AE-9C54-4F923A9DE5F3Q34467407-85C2169C-3125-414F-A9D6-0407F70F14F7Q35604412-EFACA771-8F8A-4123-B779-C15C6BF920F2Q36966944-AA1D5816-D6E1-4EF9-AA2C-7D4B414C5A74Q38737617-2A36726E-6C6B-4676-B22A-E758D6A1E7CBQ42563449-1DC521E0-C881-43D2-A48F-B1E9B25F752BQ48327884-6A581B14-D00B-4748-A986-B3F082A7B227
P2860
Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
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name
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@en
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
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type
label
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@en
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@nl
prefLabel
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@en
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@nl
P2860
P50
P1433
P1476
Transmembrane helix 12 plays a ...... ion and drug binding in ABCB1.
@en
P2093
Emily Crowley
P2860
P304
P356
10.1111/J.1742-4658.2010.07789.X
P407
P577
2010-08-20T00:00:00Z