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MIFlowCyt: the minimum information about a Flow Cytometry ExperimentDelay of T cell senescence by caloric restriction in aged long-lived nonhuman primatesAcute systemic DNA damage in youth does not impair immune defense with agingSultam Thiourea Inhibition of West Nile VirusWest Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and ApoptosisWest Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of v 3 IntegrinWest Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier FunctionKey role of T cell defects in age-related vulnerability to West Nile virusNaïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirusDysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans.Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells.Translational research in immune senescence: assessing the relevance of current models.Immune response to the West Nile virus in aged non-human primates.Increased efficiency of phorbol ester-induced lytic reactivation of Kaposi's sarcoma-associated herpesvirus during S phaseSex differences in T-lymphocyte tissue infiltration and development of angiotensin II hypertension.Functional CD8 T cell memory responding to persistent latent infection is maintained for life.Histone deacetylation critically determines T cell subset radiosensitivity.Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infectionsEvolution of the antigen-specific CD8+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire.Immune memory and aging: an infinite or finite resource?Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replicationDiversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens.Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging.IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signalingAcute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses.Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques.Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors.Report from the second cytomegalovirus and immunosenescence workshop.The many important facets of T-cell repertoire diversity.The role of mhc polymorphism in anti-microbial resistance.Induction of the cellular microRNA, Hs_154, by West Nile virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors.Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.T cell aging: naive but not young.Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus MacaquesMice and flies and monkeys too: caloric restriction rejuvenates the aging immune system of non-human primates.
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description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Žugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Žugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Zugich
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Janko Nikolich-Žugich
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P106
P1153
6701641820
P21
P31
P496
0000-0001-5830-5323