about
Bridging the synaptic gap: neuroligins and neurexin I in Apis melliferaDynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyCThe structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenesIn crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesteraseMalonate-bound structure of the glycerophosphodiesterase fromEnterobacter aerogenes(GpdQ) and characterization of the native Fe2+metal-ion preferenceEvolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 seriesIdentification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradationStructure and function of an insect -carboxylesterase ( Esterase7) associated with insecticide resistanceA 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site MutagenesisDiminishing returns and tradeoffs constrain the laboratory optimization of an enzyme300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme StabilizationCrystal structure of the mouse interleukin-3 β-receptor: insights into interleukin-3 binding and receptor activationIron(III) located in the dinuclear metallo-β-lactamase IMP-1 by pseudocontact shiftsSequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in MycobacteriaAncestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding ProteinsConformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic EfficiencyEvolution of Protein Quaternary Structure in Response to Selective Pressure for Increased ThermostabilityMapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic CrystallographyRv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosisConformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational EffectsThe role of protein dynamics in the evolution of new enzyme functionReverse evolution leads to genotypic incompatibility despite functional and active site convergenceMining electron density for functionally relevant protein polysterism in crystal structures.Structural reconstruction of protein ancestry.Predicting X-ray diffuse scattering from translation-libration-screw structural ensembles.Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source.Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution.Biochemistry of microbial degradation of hexachlorocyclohexane and prospects for bioremediation.Mycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism.Catalytic improvement and evolution of atrazine chlorohydrolase.Kinetics and efficacy of an organophosphorus hydrolase in a rodent model of methyl-parathion poisoning.Kinetic and sequence-structure-function analysis of known LinA variants with different hexachlorocyclohexane isomers.Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides.Intramolecular epistasis and the evolution of a new enzymatic functionEvolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron.Use of OpdA, an organophosphorus (OP) hydrolase, prevents lethality in an African green monkey model of acute OP poisoningConstruction of a robust and sensitive arginine biosensor through ancestral protein reconstructionThe enzymatic basis for pesticide bioremediation.The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes.Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis.
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P50
description
hulumtues
@sq
researcher
@en
հետազոտող
@hy
name
Colin Jackson
@ast
Colin Jackson
@en
Colin Jackson
@es
Colin Jackson
@nl
Colin Jackson
@sl
Колин Джексон
@ru
type
label
Colin Jackson
@ast
Colin Jackson
@en
Colin Jackson
@es
Colin Jackson
@nl
Colin Jackson
@sl
Колин Джексон
@ru
prefLabel
Colin Jackson
@ast
Colin Jackson
@en
Colin Jackson
@es
Colin Jackson
@nl
Colin Jackson
@sl
Колин Джексон
@ru
P106
P21
P31
P496
0000-0001-6150-3822