Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.
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Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases.Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domainNicastrin guards Alzheimer's gateCrystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid ProteolysisAn Inducible Reconstitution System for the Real-Time Kinetic Analysis of Protease Activity and Inhibition Inside the Membrane.Enzymatic Assays for Studying Intramembrane Proteolysis.Structural insights into adiponectin receptors suggest ceramidase activity.Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog.Involvement of a conserved GFG motif region in substrate binding by RseP, an Escherichia coli S2P protease.Bacillus subtilis Intramembrane Protease RasP Activity in Escherichia coli and In Vitro.Membrane properties that shape the evolution of membrane enzymes.
P2860
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P2860
Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Intramembrane proteolysis of β ...... is an unusually slow process.
@en
Intramembrane proteolysis of β ...... is an unusually slow process.
@nl
type
label
Intramembrane proteolysis of β ...... is an unusually slow process.
@en
Intramembrane proteolysis of β ...... is an unusually slow process.
@nl
prefLabel
Intramembrane proteolysis of β ...... is an unusually slow process.
@en
Intramembrane proteolysis of β ...... is an unusually slow process.
@nl
P2093
P2860
P1433
P1476
Intramembrane proteolysis of β ...... is an unusually slow process.
@en
P2093
Amelie Ebke
Edith Winkler
Frits Kamp
Harald Steiner
Johannes Trambauer
P2860
P304
P356
10.1016/J.BPJ.2014.12.045
P407
P577
2015-03-01T00:00:00Z