Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation. - sprookjes - yvandenbroek - TriplyDB

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

http://www.wikidata.org/entity/Q42812146

about

New Auroras on the Roles of the Chromosomal Passenger Complex in Cytokinesis: Implications for Cancer Therapies Epstein-Barr Virus: Diseases Linked to Infection and Transformation Aurora kinase inhibitors--rising stars in cancer therapeutics?A new aurora in anaplastic thyroid cancer therapy.Aurora-B regulates RNA methyltransferase NSUN2 Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia.Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cells Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia.Phase I dose escalation study of MK-0457, a novel Aurora kinase inhibitor, in adult patients with advanced solid tumors.Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors Aurora kinase-C-T191D is constitutively active mutant.Phase I study of the Aurora B kinase inhibitor barasertib (AZD1152) to assess the pharmacokinetics, metabolism and excretion in patients with acute myeloid leukemia.Aurora kinase targeting in lung cancer reduces KRAS-induced transformation.Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.Target validation and biomarker identification in oncology : the example of aurora kinases.Aurora kinase inhibitors: progress towards the clinic Mitosis as an anti-cancer drug target.Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia.Anticancer activity of the Aurora A kinase inhibitor MK-5108 in non-small-cell lung cancer (NSCLC) in vitro as monotherapy and in combination with chemotherapies.Aurora B expression as a prognostic indicator and possible therapeutic target in oral squamous cell carcinoma.Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer.Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling.The role of Aurora B expression in non-tumor liver tissues of patients with hepatocellular carcinoma.AURKB and MAPK involvement in the regulation of the early stages of mouse zygote development.

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P2860

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

http://www.wikidata.org/entity/Q42812146

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

2005年论文

@zh

2005年论文

@zh-cn

name

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@en

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@nl

type

label

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@en

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@nl

prefLabel

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@en

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

@nl

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Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation

@en

P2093

Akifumi Kanda

http://www.w3.org/2001/XMLSchema#string

Hidehiko Kawai

http://www.w3.org/2001/XMLSchema#string

Masaaki Tatsuka

http://www.w3.org/2001/XMLSchema#string

Shiho Suto

http://www.w3.org/2001/XMLSchema#string

Sunao Sato

http://www.w3.org/2001/XMLSchema#string

Takashi Takata

http://www.w3.org/2001/XMLSchema#string

P2860

Control of apoptosis and mitotic spindle checkpoint by survivin

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis

Aurora B regulates MCAK at the mitotic centromere

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

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7266-7272

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scholarly article

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10.1038/SJ.ONC.1208884

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49

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24

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Shojiro Kitajima

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2005-11-01T00:00:00Z

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7716658

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1044515851

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16027732

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