Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics. - sprookjes - yvandenbroek - TriplyDB

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

http://www.wikidata.org/entity/Q42824517

about

High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase Circadian clock control of the cellular response to DNA damage Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer Casein kinase 1 delta regulates the pace of the mammalian circadian clock Post-transcriptional control of the mammalian circadian clock: implications for health and disease Reciprocal Control of the Circadian Clock and Cellular Redox State - a Critical Appraisal The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma Molecular architecture of the mammalian circadian clock Time-of-day- and light-dependent expression of ubiquitin protein ligase E3 component N-recognin 4 (UBR4) in the suprachiasmatic nucleus circadian clock Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex Chemical chronobiology: Toward drugs manipulating time.Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.Transcriptional architecture and chromatin landscape of the core circadian clock in mammals The genetics of mammalian circadian order and disorder: implications for physiology and disease Quantification of circadian rhythms in single cells.Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats.Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha Period 2 mutation accelerates ApcMin/+ tumorigenesis.Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.Diversity of human clock genotypes and consequences.CULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clock Metabolic and nontranscriptional circadian clocks: eukaryotes.Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination Small molecule modifiers of circadian clocks.Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability Role of phosphorylation in the mammalian circadian clock.Functional analysis of Casein Kinase 1 in a minimal circadian system Intracellular and intercellular processes determine robustness of the circadian clock.Genetic insights on sleep schedules: this time, it's PERsonal.Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.Genetics of circadian rhythms in Mammalian model organisms.A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta.

P2860

Q21563543-674547DB-0CDC-44A0-829E-1850A8C82531 Q24296171-9B61F447-0575-45F9-B62F-C29380F8DBAB Q24304122-C2289A8B-979B-4245-BBEF-9A494A7AFEBC Q24602881-96AF4EDC-E5E2-4721-B31C-DC8FD53106A4 Q24648025-A5CCD26A-C40E-4BA2-8FF8-FFBCCBA2D0CC Q24654667-0EEF0433-C872-452E-85E9-014F78E71DDA Q26750780-74E78D6E-8CB5-49DB-B282-4DD457CE3F7E Q26774796-77F00625-EA83-4DA9-A9D8-72FB77526924 Q26782159-48CDFF18-F0BF-432F-95D9-BCEC06A23B1D Q27004052-A23C07B1-D28E-4088-8892-5F50D8600E87 Q27318176-7F012359-810C-4BE5-BB51-577A1AF3B426 Q27679392-FA2181B3-342F-414A-BD65-7C9BB23A62E0 Q27687867-796B7BA6-51F9-4266-A920-B2CD0543C287 Q28512569-ED0B5544-DC86-4509-853A-57E07C345D8E Q28582355-50A4E218-3F57-400C-998A-B29880041A8E Q28588540-C360001F-6EA7-4EB5-A632-AC199DD34A60 Q29347109-718659C5-9FF3-45C0-82CC-F8EA7DD60400 Q29616252-C1F3B052-8CD2-46AD-9ABF-8C8F02C5B094 Q29616366-AE2A99BF-ACFB-4B23-B808-821D0783DC29 Q30946744-105DCB7D-1666-44BF-BF81-68BFE201540E Q33701868-65471465-CC26-46F1-BE8F-CF4E3E5B8A42 Q33722806-36CAA79F-D699-4078-87EF-EF02751AEB11 Q33815603-5AEB6043-F679-4B28-A9A7-D925502A545A Q33953327-62F5992D-4456-4086-AD57-C02CF0CF2B20 Q34060495-E25E8491-9848-428E-93DE-B28EF5F8A5D6 Q34147624-FEE316DE-9471-48C5-B1F6-1191DFC39FBD Q34214140-A1D608F3-1912-4849-996C-1E91982C48E7 Q34373827-7E0EC7E3-D6D6-4E8E-A586-0874F221DBD4 Q34408902-A32BA90F-3B3D-4A45-A909-8628B04DCF57 Q34460462-9AC378CB-4232-4C85-B34C-AE4BF9F5EE57 Q34480532-3F21E539-BB59-4954-BE0F-A1CE3A4E4044 Q34752680-5B831BA4-07D4-42CD-95E7-651F15FD740F Q34770736-F613A6A2-143B-4A20-A0AC-64742783BCCC Q34921771-3546689B-A2A4-453F-857F-C6BF4AC046E3 Q35051662-E1416942-9E2C-484A-8905-8B1E5A623C8A Q36405856-4830B466-19D7-4DCF-80BA-FB529E1AB076 Q36684795-B5FE6857-444B-4B57-8716-19E2A305F93B Q36969070-07C30542-318F-487C-BF8A-2F189B9F98CD Q37005459-211C0AE0-BFAC-407B-A806-DB44BBD544E5 Q37023129-4B8554BC-0A14-42A8-9238-AAF93B3F096C

P2860

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

http://www.wikidata.org/entity/Q42824517

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@en

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@nl

type

label

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@en

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@nl

prefLabel

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@en

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@nl

P1433

Q42824517-18316F89-4ABD-493F-B605-E89684F4873D

P1476

Q42824517-FE4DBE10-928C-402F-ADE2-53D2049D4EA8

P2093

Q42824517-00447327-E305-4671-82C9-D569489B011F

Q42824517-4EA5AFCE-8955-430E-9FD0-815532ED847D

Q42824517-67FE8305-2DB3-4B09-A1FC-F0F97B7F3D67

Q42824517-A87F2376-8B09-4AF5-B841-D5E61799FDE3

Q42824517-B67742AE-EEFC-44F0-8550-DBAB2F48901B

Q42824517-BC510395-079F-4145-AC0A-A87CF3D28C9C

P2860

Q42824517-014D58CC-2BD7-45BD-A0F2-1E4F8DE80DE8

Q42824517-0287A11F-EE75-4583-8B5B-BF93095EC68E

Q42824517-033CDF60-B4D1-4029-AEB9-B12F95465312

Q42824517-0ACDA877-4959-485D-A191-BC4417BB89EC

Q42824517-0B5DEC52-2D4B-4B2C-9A49-72899CB89A0F

Q42824517-0C3ECCE4-CD72-44CF-B100-44E52E475D2A

Q42824517-10BE419D-1150-4C67-BB79-D8AC38A34E9E

Q42824517-11C0FC3D-FA1F-4019-B8B6-ADB4831D8B06

Q42824517-16FC33E5-43DB-4F55-8D54-EE9176749B2D

Q42824517-1D61EC11-3824-4161-82C2-D68D1C2A26CC

P304

Q42824517-E8217544-958E-44E2-9F9D-11E3725289BB

P31

Q42824517-3A2AE559-54F2-4DF6-8D0F-235722E344B7

P356

Q42824517-D529F3C3-C823-4E0C-B6FC-3493D0A714B3

P433

Q42824517-60045EC0-0671-432B-B4E8-E359287ECE01

P478

Q42824517-0C3EF640-9D6C-4DA8-802A-13990F926635

P50

Q42824517-FF84E60D-CA47-42BA-8AF3-45227334B137

P577

Q42824517-4E9B604F-4B4F-46A9-BDEC-52E9DB677E60

P5875

Q42824517-44F07BCE-F51D-48A2-9AE6-11EAB840128C

P698

Q42824517-20CE3EB2-0976-4557-823B-EE2D7F710C9C

P921

Q42824517-B4A7060E-8DE6-4937-8EEB-9E810A73A49A

P356

0748730407303926

P1433

Journal of Biological Rhythms

P1476

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

@en

P2093

Achim Kramer

http://www.w3.org/2001/XMLSchema#string

Bert Maier

http://www.w3.org/2001/XMLSchema#string

Hanspeter Herzel

http://www.w3.org/2001/XMLSchema#string

Katja Vanselow

http://www.w3.org/2001/XMLSchema#string

Nadine Thierfelder

http://www.w3.org/2001/XMLSchema#string

Silke Reischl

http://www.w3.org/2001/XMLSchema#string

P2860

SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon

Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)

The period length of fibroblast circadian gene expression varies widely among human individuals

Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.

Posttranslational mechanisms regulate the mammalian circadian clock.

P304

375-386

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1177/0748730407303926

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

Pål O. Westermark

P577

2007-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5967101

http://www.w3.org/2001/XMLSchema#string

P698

17876059

http://www.w3.org/2001/XMLSchema#string

P921

circadian rhythm