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Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiologyActivation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstrictionPulmonary arterial dysfunction in insulin resistant obese Zucker rats.The flavonoid quercetin reverses pulmonary hypertension in rats.The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells.HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstrictionPPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells.Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials.Role of K+ channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways.Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain.Response of chicken ductus arteriosus to hypercarbic and normocarbic acidosis.Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria.Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries.Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.Cytosolic Ca2+ and phosphoinositide hydrolysis linked to constitutively active alpha 1D-adrenoceptors in vascular smooth muscle.Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta.Pulmonary vascular dysfunction induced by high tidal volume mechanical ventilation.Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats.Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle.Different patterns of pulmonary vascular disease induced by type 1 diabetes and moderate hypoxia in rats.Type 1 diabetes-induced hyper-responsiveness to 5-hydroxytryptamine in rat pulmonary arteries via oxidative stress and induction of cyclooxygenase-2.Postnatal maturation of phosphodiesterase 5 (PDE5) in piglet pulmonary arteries: activity, expression, effects of PDE5 inhibitors, and role of the nitric oxide/cyclic GMP pathway.Soluble guanylyl cyclase during postnatal porcine pulmonary maturation.Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction.Maturation of O2 sensing and signaling in the chicken ductus arteriosus.Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats.Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.Developmental changes in the effects of prostaglandin E2 in the chicken ductus arteriosus.Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity.Relaxant effects of the soluble guanylate cyclase activator and NO sensitizer YC-1 in piglet pulmonary arteries.Hypoxic pulmonary vasoconstriction, carotid body function and erythropoietin production in adult rats perinatally exposed to hyperoxia.Effects of Quercetin in a Rat Model of Hemorrhagic Traumatic Shock and Reperfusion.Role of tetrahydrobiopterin in pulmonary vascular remodelling associated with pulmonary fibrosis.Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction.Characterisation and regulation of wild type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertensionCeramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteriesCeramide and Regulation of Vascular ToneActivation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Angel Cogolludo
@ast
Angel Cogolludo
@en
Angel Cogolludo
@es
Angel Cogolludo
@nl
type
label
Angel Cogolludo
@ast
Angel Cogolludo
@en
Angel Cogolludo
@es
Angel Cogolludo
@nl
prefLabel
Angel Cogolludo
@ast
Angel Cogolludo
@en
Angel Cogolludo
@es
Angel Cogolludo
@nl
P106
P1153
6602609050
P21
P31
P496
0000-0002-1382-1698