about
Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1)--distinct characteristics in neuronsRelevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.The patatin-like lipase family in Gallus gallus.TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancerBRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanineSuppression of BRCA1 sensitizes cells to proteasome inhibitors.Dasatinib reversibly disrupts endothelial vascular integrity by increasing non-muscle myosin II contractility in a ROCK-dependent manner.High Throughput siRNA Screening Using Reverse Transfection.HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia.Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.Precision Cancer Medicine in the Acoustic Dispensing Era: Ex Vivo Primary Cell Drug Sensitivity Testing.Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.Avian phospholipid transfer protein causes HDL conversion without affecting cholesterol efflux from macrophages.APECED-causing mutations in AIRE reveal the functional domains of the protein.Methods for High-throughput Drug Combination Screening and Synergy Scoring.Identification of an aspartylglucosaminidase-like protein in the venom of the parasitic wasp Asobara tabida (Hymenoptera: Braconidae).The high throughput biomedicine unit at the institute for molecular medicine Finland: high throughput screening meets precision medicine.Combined gene essentiality scoring improves the prediction of cancer dependency mapsNetwork pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancerPatient-derived organoids from multiple colorectal cancer liver metastases reveal moderate intra-patient pharmacotranscriptomic heterogeneityDevelopment of FRET-based high-throughput screening for viral RNase III inhibitors
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
@hy
name
Jani Saarela
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Jani Saarela
@en
Jani Saarela
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Jani Saarela
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Jani Saarela
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type
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Jani Saarela
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Jani Saarela
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Jani Saarela
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Jani Saarela
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Jani Saarela
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prefLabel
Jani Saarela
@ast
Jani Saarela
@en
Jani Saarela
@es
Jani Saarela
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Jani Saarela
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P106
P21
P31
P496
0000-0001-7306-7175