Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U.
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Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanineActivity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegalovirusesMode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovirEffects of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpesvirus compound, on synthesis of macromolecules in herpes simplex virus-infected cellsIdentification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.Targeting of an inducible toxic phenotype in animal cellsSusceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovirThree-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudineMetabolic activation of 9([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human lymphoblastoid cell lines infected with Epstein-Barr virusAntiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infectionThe enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerasesTAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the acute local phase of herpes simplex virus-induced skin infections in mice and the establishment of latency.Comparison of the modes of antiviral action of 2'-nor-deoxyguanosine and its cyclic phosphate, 2'-nor-cyclic GMP.A mouse model for X-linked adrenoleukodystrophy.Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.Functional expression of a cloned herpes simplex virus type 1 DNA polymerase geneSensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locusUse of microorganisms for the study of drug metabolism: an update.Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibitionGene Targeting in Neuroendocrinology.Chemotherapy of herpesvirus infections.Effect of duration and intensity of ganciclovir exposure on lymphoblastoid cell toxicity.Characterization of the Epstein-Barr virus-encoded thymidine kinase expressed in heterologous eucaryotic and procaryotic systems.Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information.Impaired mismatch extension by a herpes simplex DNA polymerase mutant with an editing nuclease defect.Cryptogenic colitis due to occult cytomegalovirus infection.2'-nor-cGMP, a new cyclic derivative of 2'NDG, inhibits HSV-1 replication in vitro and in the mouse keratitis model.Efficacy of BW759 (9-[[2-hydroxy-1(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits.
P2860
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P2860
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@en
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@nl
type
label
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@en
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@nl
prefLabel
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@en
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@nl
P2093
P2860
P356
P1476
Inhibition of cellular alpha D ...... by the triphosphate of BW759U.
@en
P2093
P2860
P304
P356
10.1128/AAC.25.2.191
P407
P577
1984-02-01T00:00:00Z