Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.
about
Thiopurine S-methyltransferase testing for averting drug toxicity: a meta-analysis of diagnostic test accuracyPharmacogenetics in inflammatory bowel diseaseFrequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositusRecent advances in the pharmacogenomics of thiopurine methyltransferase.The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics.Pharmacogenetics in diverse ethnic populations--implications for drug discovery and development.Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.Comparative pharmacogenetic analysis of risk polymorphisms in Caucasian and Vietnamese children with acute lymphoblastic leukemia: prediction of therapeutic outcome?Therapeutic drug monitoring in patients with inflammatory bowel diseaseDrug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance.Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel diseaseThiopurine S-methyltransferase testing for averting drug toxicity in patients receiving thiopurines: a systematic review.Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine.High-resolution melting analysis of the TPMT gene: a study in the Polish population.Genetics of inflammatory bowel disease: current status and future directions.Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.Nomenclature for alleles of the thiopurine methyltransferase gene.PhRMA white paper on ADME pharmacogenomics.Transcriptional regulation and pharmacogenomics.Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia.Interindividual variability in TPMT enzyme activity: 10 years of experience with thiopurine pharmacogenetics and therapeutic drug monitoring.Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease.One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.Genetic polymorphisms of NQO1, CYP1A1 and TPMT and susceptibility to acute lymphoblastic leukemia in a Tunisian population.Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods.Gene polymorphisms involved in manifestation of leucopenia, digestive intolerance, and pancreatitis in azathioprine-treated patients.Functional analysis of the role of the TPMT gene promoter VNTR polymorphism in TPMT gene transcription.Thiopurine S-methyltransferase (TPMT) genetic polymorphisms in Mexican newborns.Start low, go slow, but don't go this way yet.Thiopurine methyltransferase polymorphisms in a Brazilian population.Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?Influence of thiopurine methyltransferase gene polymorphism on Egyptian children with acute lymphoblastic leukaemia.Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity.Thiopurine methyltransferase (TPMT) activity and adverse effects of azathioprine in inflammatory bowel disease: long-term follow-up study of 394 patients.TPMT gene expression is increased during maintenance therapy in childhood acute lymphoblastic leukemia patients in a TPMT gene promoter variable number of tandem repeat-dependent manner.6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.The frequency and distribution of thiopurine S-methyltransferase alleles in south Iranian population.TPMT genotype and its clinical implication in renal transplant recipients with azathioprine treatment.Thiopurine methyltransferase activity in a Spanish population sample: decrease of enzymatic activity in multiple sclerosis patients
P2860
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P2860
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Genotypic and phenotypic analy ...... PMT) in a European population.
@en
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene
@nl
type
label
Genotypic and phenotypic analy ...... PMT) in a European population.
@en
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene
@nl
prefLabel
Genotypic and phenotypic analy ...... PMT) in a European population.
@en
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene
@nl
P2093
P2860
P356
P1476
Genotypic and phenotypic analy ...... TPMT) in a European population
@en
P2093
Chevalier D
Colombel JF
Debuysere H
Lafitte JJ
Lhermitte M
P2860
P304
P356
10.1038/SJ.BJP.0702152
P407
P577
1998-10-01T00:00:00Z