Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
about
Altered cardiac electrophysiology and SUDEP in a model of Dravet syndromeNa⁺ transport in the normal and failing heart - remember the balanceThe channelopathies: novel insights into molecular and genetic mechanisms of human diseasePathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndromeScn3b knockout mice exhibit abnormal ventricular electrophysiological propertiesMolecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of actionMolecular and genetic basis of sudden cardiac deathCardiac sodium channel Nav1.5 mutations and cardiac arrhythmiaMaturation status of sarcomere structure and function in human iPSC-derived cardiac myocytesStochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic loadLate Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial FibrillationAKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophyAberrant sodium influx causes cardiomyopathy and atrial fibrillation in miceSlowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a.A simulation study of the effects of cardiac anatomy in ventricular fibrillationMouse models of long QT syndrome.Characterization of the cardiac sodium channel SCN5A mutation, N1325S, in single murine ventricular myocytes.Mutation-specific risk in two genetic forms of type 3 long QT syndrome.The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients.New iPSC for old long QT syndrome modeling: putting the evidence into perspective.p.Y1449C SCN5A mutation associated with overlap disorder comprising conduction disease, Brugada syndrome, and atrial flutter.Regulated and aberrant glycosylation modulate cardiac electrical signaling.Inherited disorders of voltage-gated sodium channels.Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3Depolarization of cardiac membrane potential synchronizes calcium sparks and waves in tissueModulation of cardiac gap junction expression and arrhythmic susceptibility.MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarizationLight phase-restricted feeding slows basal heart rate to exaggerate the type-3 long QT syndrome phenotype in mice.Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndromeSelective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmiasMechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo.Calcium and arrhythmogenesis.Modulation of the late sodium current by ATX-II and ranolazine affects the reverse use-dependence and proarrhythmic liability of IKr blockade.Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs.Triple threat: the Na+/Ca2+ exchanger in the pathophysiology of cardiac arrhythmia, ischemia and heart failure.Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitroAltered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.Computational biology in the study of cardiac ion channels and cell electrophysiology.
P2860
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P2860
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@en
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@nl
type
label
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@en
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@nl
prefLabel
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@en
Abrupt rate accelerations or p ...... n mice with long-QT3 syndrome.
@nl
P2093
P50
P356
P1433
P1476
Abrupt rate accelerations or p ...... in mice with long-QT3 syndrome
@en
P2093
Carmeliet E
Carmeliet P
Compernolle V
Dewerchin M
Dugarmaa S
Rossenbacker T
P2888
P304
P356
10.1038/NM0901-1021
P407
P577
2001-09-01T00:00:00Z