about
The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancerThe prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancerShear-wave elastography and greyscale assessment of palpable probably benign masses: is biopsy always required?MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism.Histological evaluation of AMPK signalling in primary breast cancerp53 mutation, deprivation and poor prognosis in primary breast cancerFGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.Landscape of somatic mutations in 560 breast cancer whole-genome sequences.Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based studyProspective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS).Quantitative shear wave ultrasound elastography: initial experience in solid breast massesp53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.High frequency of complex TP53 mutations in CNS metastases from breast cancer.Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification.A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer.Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcomComparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays.Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancerThe Informatics Challenges Facing Biobanks: A Perspective from a United Kingdom Biobanking Network.Differential p53 protein expression in breast cancer fine needle aspirates: the potential for in vivo monitoringMultiparameter DNA content analysis identifies distinct groups in primary breast cancer.A prognostic index for operable, node-negative breast cancer.A candidate molecular signature associated with tamoxifen failure in primary breast cancerMeta-analysis of sentinel node biopsy in ductal carcinoma in situ of the breast.Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.TP53 drives invasion through expression of its Δ133p53β variant.CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study.Involved anterior margins after breast conserving surgery: is re-excision required?Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors.The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example.Biomarker discordance: prospective and retrospective evidence that biopsy of recurrent disease is of clinical utility.Macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment: review of pathological issues and suggested approaches.Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy.Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status.Stiffness at shear-wave elastography and patient presentation predicts upgrade at surgery following an ultrasound-guided core biopsy diagnosis of ductal carcinoma in situ.Counting alleles to predict recurrence of early-stage colorectal cancers.
P50
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description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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Colin A Purdie
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P106
P21
P31
P496
0000-0002-1258-4010