PTF1A related regulatory pathway - sprookjes - yvandenbroek - TriplyDB

PTF1A related regulatory pathway

PTF1A related regulatory pathway

http://www.wikidata.org/entity/Q44015398

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PTF1A related regulatory pathway

http://www.wikidata.org/entity/Q44015398

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By summarizing published data ...... hole sight in early mouse d...

@en

name

PTF1A related regulatory pathway

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type

label

PTF1A related regulatory pathway

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prefLabel

PTF1A related regulatory pathway

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P1476

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P1476

PTF1A related regulatory pathway

@en

P2093

Martina Kutmon

http://www.w3.org/2001/XMLSchema#string

P2410

WP4147

http://www.w3.org/2001/XMLSchema#string

P2860

Wnt/beta-catenin signaling is required for development of the exocrine pancreas

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.

Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas.

Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex.

p/CAF modulates the activity of the transcription factor p48/Ptf1a involved in pancreatic acinar differentiation.

Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III

Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development

An endothelial-mesenchymal relay pathway regulates early phases of pancreas development

P2888

P31

biological pathway

P50

Martina Summer-Kutmon

P527

P703