Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.
about
Dysregulated metabolism contributes to oncogenesisTCA Cycle (aka Krebs or citric acid cycle)Medium-chain fatty acids as metabolic therapy in cardiac diseaseQuiescent fibroblasts exhibit high metabolic activity.Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolismTriiodothyronine facilitates weaning from extracorporeal membrane oxygenation by improved mitochondrial substrate utilization.A giant molecular proton pump: structure and mechanism of respiratory complex I.Cardiac anaplerosis in health and disease: food for thought.A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Reductive carboxylation supports growth in tumour cells with defective mitochondria.Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathwayReverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells.Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.Isocitrate dehydrogenase mutations in gliomasWhat a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.Mitochondrial alterations and oxidative stress in an acute transient mouse model of muscle degeneration: implications for muscular dystrophy and related muscle pathologies.Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium.Elimination of NADPH oxidase activity promotes reductive stress and sensitizes the heart to ischemic injury.Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux.Cardiac mitochondrial proteomic expression in inbred rat strains divergent in survival time after hemorrhage.Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function.Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase.Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line.The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells.13C-flux analysis reveals NADPH-balancing transhydrogenation cycles in stationary phase of nitrogen-starving Bacillus subtilis.Cytosolic and mitochondrial isoforms of NADP+-dependent isocitrate dehydrogenases are expressed in cultured rat neurons, astrocytes, oligodendrocytes and microglial cells.Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts.Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid.Cardioprotective effect of L-glutamate in obese type 2 diabetic Zucker fatty rats.Intra-uterine growth restriction and the programming of left ventricular remodelling in female rats.Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion.Cardioprotection by L-glutamate during postischaemic reperfusion: reduced infarct size and enhanced glycogen resynthesis in a rat insulin-free heart model.
P2860
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P2860
Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Reverse flux through cardiac NADP
@nl
Reverse flux through cardiac N ...... e under normoxia and ischemia.
@en
type
label
Reverse flux through cardiac NADP
@nl
Reverse flux through cardiac N ...... e under normoxia and ischemia.
@en
prefLabel
Reverse flux through cardiac NADP
@nl
Reverse flux through cardiac N ...... e under normoxia and ischemia.
@en
P2093
P1476
Reverse flux through cardiac N ...... e under normoxia and ischemia.
@en
P2093
Bertrand Bouchard
Blandine Comte
Christine Des Rosiers
Geneviève Vincent
Mohamed Benderdour
P304
P356
10.1152/AJPHEART.00287.2002
P577
2002-10-01T00:00:00Z