Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
about
A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1)Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factorNP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry.Platelet integrins and immunoreceptors.P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic windowThe human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.Collagen promotes sustained glycoprotein VI signaling in platelets and cell lines.Glycoprotein VI/Fc receptor gamma chain-independent tyrosine phosphorylation and activation of murine platelets by collagen.Facilitating roles of murine platelet glycoprotein Ib and alphaIIbbeta3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation.Differential roles of integrins alpha2beta1 and alphaIIbbeta3 in collagen and CRP-induced platelet activation.Evaluation of the role of platelet integrins in fibronectin-dependent spreading and adhesion.The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities.Von Willebrand factor present in fibrillar collagen enhances platelet adhesion to collagen and collagen-induced platelet aggregation.Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets.The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen.
P2860
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P2860
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@en
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@nl
type
label
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@en
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@nl
prefLabel
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@en
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@nl
P2860
P1476
Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators.
@en
P2093
Atkinson BT
P2860
P304
P356
10.1046/J.1538-7836.2003.00245.X
P577
2003-06-01T00:00:00Z