about
corticotropinbeta-melanocyte-stimulating hormonegamma-melanocyte-stimulating hormonealpha-melanocyte-stimulating hormonevasoactive intestinal peptideOlfactory Signaling PathwayLiganded Gs-activating GPCRs bind inactive heterotrimeric GsLiganded Gs-activating GPCR acts as a GEF for GsThe Ligand:GPCR:Gs complex dissociatesAdenylate cyclase converts ATP to 3';5'-cyclic AMP (cAMP) and pyrophosphatecAMP degradation by PhosphodiesterasesG alpha (s) auto-inactivates by hydrolysing GTP to GDPInactive G alpha (s) reassociates with G beta:gammaADRB2 in ADRB2:GRK complex is phosphorylatedADRB2:Catecholamine binds ARRB1; ARRB2GRKs bind ADRB2:CatecholamineADRB2:GRK complex dissociates to Phosphorylated ADRB2
P361
Q185690-010c9c69-4e76-241f-1b39-e204d46c95d1Q20707037-8b6843d5-4c93-2cc0-55ae-3f21d0b65795Q20707046-8cb3b2d7-4bf7-c27d-9cf3-c2bc1471597cQ4063639-1b9fff74-47bd-f693-d0e2-e8cf4b5cbe04Q414964-03b0aede-4e2d-3b09-da25-a77da1dffbefQ45318190-D32283D5-8CEF-4B93-BAC0-AD940A4D664CQ50298410-CB43ED40-4F18-4F4A-8655-1B88584F3466Q50298411-2EB17ED3-247C-4EC7-89D6-63DBC208C003Q50298412-92AFE971-803D-4619-B5CC-383E0C4406E7Q50298413-EDF3A930-DF44-4DD9-8903-674FB26D7241Q50298414-0F364CC6-A7A8-42AC-B808-3CA923373EEAQ50298415-65735A6A-9A08-4795-B968-6F31C5C306DBQ50298416-9EBD4841-ED4B-4689-AC8E-D83A5E67FC75Q50298417-64EF3DA5-D9FA-47CD-B285-151F95B40DC7Q50298418-4170A141-2D4E-430B-ACEE-1B862B5B1DE4Q50298419-A3C49A2C-E0DB-4124-8475-7B37FFE6A819Q50298420-45CA50D5-6189-4BB0-9ABE-2AA4E18B9FEC
P361
description
An instance of the biological pathway G alpha (s) signalling events in Homo sapiens
@en
name
G alpha (s) signalling events
@en
type
label
G alpha (s) signalling events
@en
prefLabel
G alpha (s) signalling events
@en
P527
P3937
R-HSA-418555