Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice.
about
Novel bile acid therapeutics for the treatment of chronic liver diseasesRoles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and DiseaseBile acid receptors and nonalcoholic fatty liver diseaseEndocrine FGFs: Evolution, Physiology, Pathophysiology, and PharmacotherapyBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerElucidating the metabolic regulation of liver regenerationBile acids as metabolic regulatorsThe role of bile salts in liver regenerationBile acid signaling and biliary functionsKey discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decadesFibroblast growth factor 15 deficiency impairs liver regeneration in mice.Bile acid flux is necessary for normal liver regeneration.The Fibroblast Growth Factor signaling pathwayBile acid signaling and liver regeneration.Enterohepatic bacterial infections dysregulate the FGF15-FGFR4 endocrine axis.Simultaneous bile duct and portal vein ligation induces faster atrophy/hypertrophy complex than portal vein ligation: role of bile acids.Development of a chemically defined medium and discovery of new mitogenic growth factors for mouse hepatocytes: mitogenic effects of FGF1/2 and PDGF.Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice.Implications of microbiota and bile acid in liver injury and regeneration.Regulation of bile acid homeostasis by the intestinal Diet1-FGF15/19 axis.Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration.Mice Abundant in Muricholic Bile Acids Show Resistance to Dietary Induced Steatosis, Weight Gain, and to Impaired Glucose MetabolismExpression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the diseaseFibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized LiversFarnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration.Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation.Validation of the peak bilirubin criterion for outcome after partial hepatectomy.Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice.Bile acid receptors as targets for drug development.In vitro culture of isolated primary hepatocytes and stem cell-derived hepatocyte-like cells for liver regeneration.Regulation of hepatocyte identity and quiescence.Obeticholic acid for the treatment of primary biliary cirrhosis.The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis.IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes.Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development.A variant of FGF19 for treatment of disorders of cholestasis and bile acid metabolismHepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.Reprogramming of mice primary hepatocytes into insulin-producing cells by transfection with multicistronic vectors.Soluble expression of disulfide bond containing proteins FGF15 and FGF19 in the cytoplasm of Escherichia coli.Role of bile acids in liver injury and regeneration following acetaminophen overdose.
P2860
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P2860
Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Identification of fibroblast g ...... section liver failure in mice.
@en
Identification of fibroblast g ...... section liver failure in mice.
@nl
type
label
Identification of fibroblast g ...... section liver failure in mice.
@en
Identification of fibroblast g ...... section liver failure in mice.
@nl
prefLabel
Identification of fibroblast g ...... section liver failure in mice.
@en
Identification of fibroblast g ...... section liver failure in mice.
@nl
P2093
P50
P1433
P1476
Identification of fibroblast g ...... section liver failure in mice.
@en
P2093
Axel R Concepcion
Eva Vicente
Haisul C Y Chang
Iker Uriarte
José Juan G Marin
Juan F Medina
Maite G Fernandez-Barrena
Maria U Latasa
Matías A Avila
P304
P356
10.1136/GUTJNL-2012-302945
P407
P50
P577
2013-01-03T00:00:00Z