Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. - sprookjes - yvandenbroek - TriplyDB

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells.

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells.

http://www.wikidata.org/entity/Q46665781

about

Nuclear import of Pin1 is mediated by a novel sequence in the PPIase domain Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins Prolyl isomerase Pin1 in cancer Understanding the role of PIN1 in hepatocellular carcinoma Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations Landscape of Pin1 in the cell cycle A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease Pin1: a molecular orchestrator in the heart.Mitotic phosphorylation of the anaphase-promoting complex inhibitory subunit Mnd2 is necessary for efficient progression through meiosis i.Dynamic regulation of Pin1 expression and function during zebrafish development.Polo-box domain: a versatile mediator of polo-like kinase function.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function Complete determination of the Pin1 catalytic domain thermodynamic cycle by NMR lineshape analysis.Some p53-binding proteins that can function as arbiters of life and death.An unusual two-step control of CPEB destruction by Pin1.Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.PKCθ-Mediated PDK1 Phosphorylation Enhances T Cell Activation by Increasing PDK1 Stability.Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.Pin1, the Master Orchestrator of Bone Cell Differentiation.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.The role of Pin1 in the development and treatment of cancer.PIN1 in breast development and cancer: a clinical perspective.Determinants for activation of the atypical AGC kinase Greatwall during M phase entry.The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Pin1, a new player in the fate of HIF-1α degradation: an hypothetical mechanism inside vascular damage as Alzheimer's disease risk factor.Comparative analysis of enzyme activities and mRNA levels of peptidyl prolyl cis/trans isomerases in various organs of wild type and Pin1-/- mice.Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.Pin1 mediates Aβ42-induced dendritic spine loss.Prolyl isomerase Pin1: a promoter of cancer and a target for therapy Pin1 Modulation in Physiological Status and Neurodegeneration. Any Contribution to the Pathogenesis of Type 3 Diabetes?Gears-In-Motion: The Interplay of WW and PPIase Domains in Pin1

P2860

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P2860

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells.

http://www.wikidata.org/entity/Q46665781

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh-hant

name

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@en

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@nl

type

label

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@en

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@nl

prefLabel

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@en

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@nl

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Journal of Biological Chemistry

P1476

Polo-like kinase 1-mediated ph ...... ubiquitination in human cells.

@en

P2093

Andrea Kramer

http://www.w3.org/2001/XMLSchema#string

Bernd Martin

http://www.w3.org/2001/XMLSchema#string

Christine Lindenau

http://www.w3.org/2001/XMLSchema#string

Frank Eckerdt

http://www.w3.org/2001/XMLSchema#string

Gunter Fischer

http://www.w3.org/2001/XMLSchema#string

Juping Yuan

http://www.w3.org/2001/XMLSchema#string

Klaus Strebhardt

http://www.w3.org/2001/XMLSchema#string

Krishna Saxena

http://www.w3.org/2001/XMLSchema#string

Manfred Kaufmann

http://www.w3.org/2001/XMLSchema#string

Sebastian Daum

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P2860

Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors

Active cyclin B1-Cdk1 first appears on centrosomes in prophase

The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

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36575-36583

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scholarly article

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10.1074/JBC.M504548200

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44

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280

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2005-08-23T00:00:00Z

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7642951

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16118204

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phosphorylation

protein ubiquitination