Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy.

Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy.

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http://www.wikidata.org/entity/Q46922239
Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugsHypoxia-Targeted Drug Q6 Induces G2-M Arrest and Apoptosis via Poisoning Topoisomerase II under HypoxiaLeveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid TumorsF-18 fluoromisonidazole for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapyHypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.A phase 1 'window-of-opportunity' trial testing evofosfamide (TH-302), a tumour-selective hypoxia-activated cytotoxic prodrug, with preoperative chemoradiotherapy in oesophageal adenocarcinoma patientsHypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas.In vivo quantification of hypoxic and metabolic status of NSCLC tumors using [18F]HX4 and [18F]FDG-PET/CT imaging.The indications and efficacy of conventional chemotherapy in primary and recurrent sarcoma.Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapyA Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model.Preclinical Benefit of Hypoxia-Activated Intra-arterial Therapy with Evofosfamide in Liver Cancer.Proteoglycan-targeting applied to hypoxia-activated prodrug therapy in chondrosarcoma: first proof-of-concept.Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
P2860

Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy.

Item
http://www.wikidata.org/entity/Q46922239
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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name
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@en
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@nl
type
label
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@en
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@nl
prefLabel
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@en
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Activity of the hypoxia-activa ...... eutic effects of chemotherapy.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921