about
Transglutaminase is a tumor cell and cancer stem cell survival factorIdentification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.Pericentrosomal localization of the TIG3 tumor suppressor requires an N-terminal hydrophilic region motif.Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors.The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane.Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation.Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.Transglutaminase 2 Is a Direct Target Gene of YAP-TAZ-Response
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Daniel Grun
@ast
Daniel Grun
@en
Daniel Grun
@es
Daniel Grun
@fr
Daniel Grun
@nl
Daniel Grun
@sl
type
label
Daniel Grun
@ast
Daniel Grun
@en
Daniel Grun
@es
Daniel Grun
@fr
Daniel Grun
@nl
Daniel Grun
@sl
prefLabel
Daniel Grun
@ast
Daniel Grun
@en
Daniel Grun
@es
Daniel Grun
@fr
Daniel Grun
@nl
Daniel Grun
@sl
P106
P1153
55986812000
P21
P31
P496
0000-0003-4261-7765